Characterisation of Insulin at the Interface Between Two Immiscible Electrolyte Solutions
The behaviour of insulin was characterised at the interface between the two immiscible electrolyte solutions (ITIES). Electroadsorbed insulin was subjected to study by Fourier transform infrared and Raman spectroscopy, to understand any secondary structure changes following electroadsorption. Follow...
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| Format: | Thesis |
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Curtin University
2019
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| Online Access: | http://hdl.handle.net/20.500.11937/80108 |
| _version_ | 1848764164038721536 |
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| author | Lamichhane, Hum Bahadur |
| author_facet | Lamichhane, Hum Bahadur |
| author_sort | Lamichhane, Hum Bahadur |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The behaviour of insulin was characterised at the interface between the two immiscible electrolyte solutions (ITIES). Electroadsorbed insulin was subjected to study by Fourier transform infrared and Raman spectroscopy, to understand any secondary structure changes following electroadsorption. Following electroadsorption, insulin showed secondary structure changes which varied with the aqueous insulin concentration. At higher concentration, significant proportions of combined ß-sheet and irregular helix structures were found, while a-helical forms were dominant at lower concentration. Raman spectroscopy was insensitive to insulin following electroadsorption. |
| first_indexed | 2025-11-14T11:15:00Z |
| format | Thesis |
| id | curtin-20.500.11937-80108 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:15:00Z |
| publishDate | 2019 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-801082020-07-22T02:06:31Z Characterisation of Insulin at the Interface Between Two Immiscible Electrolyte Solutions Lamichhane, Hum Bahadur The behaviour of insulin was characterised at the interface between the two immiscible electrolyte solutions (ITIES). Electroadsorbed insulin was subjected to study by Fourier transform infrared and Raman spectroscopy, to understand any secondary structure changes following electroadsorption. Following electroadsorption, insulin showed secondary structure changes which varied with the aqueous insulin concentration. At higher concentration, significant proportions of combined ß-sheet and irregular helix structures were found, while a-helical forms were dominant at lower concentration. Raman spectroscopy was insensitive to insulin following electroadsorption. 2019 Thesis http://hdl.handle.net/20.500.11937/80108 Curtin University fulltext |
| spellingShingle | Lamichhane, Hum Bahadur Characterisation of Insulin at the Interface Between Two Immiscible Electrolyte Solutions |
| title | Characterisation of Insulin at the Interface Between Two Immiscible Electrolyte Solutions |
| title_full | Characterisation of Insulin at the Interface Between Two Immiscible Electrolyte Solutions |
| title_fullStr | Characterisation of Insulin at the Interface Between Two Immiscible Electrolyte Solutions |
| title_full_unstemmed | Characterisation of Insulin at the Interface Between Two Immiscible Electrolyte Solutions |
| title_short | Characterisation of Insulin at the Interface Between Two Immiscible Electrolyte Solutions |
| title_sort | characterisation of insulin at the interface between two immiscible electrolyte solutions |
| url | http://hdl.handle.net/20.500.11937/80108 |