How do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain?
Since the advent of anatomical brain imaging analysis techniques, numerous reports have shown altered regional brain anatomy in individuals with various chronic pain conditions. While early reports of increased regional brain volumes in taxi drivers and pianists were simply interpreted as responses...
| Main Authors: | , |
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| Format: | Journal Article |
| Language: | English |
| Published: |
2016
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/79567 |
| _version_ | 1848764075943657472 |
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| author | Henderson, L.A. Prieto, Flavia |
| author_facet | Henderson, L.A. Prieto, Flavia |
| author_sort | Henderson, L.A. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Since the advent of anatomical brain imaging analysis techniques, numerous reports have shown altered regional brain anatomy in individuals with various chronic pain conditions. While early reports of increased regional brain volumes in taxi drivers and pianists were simply interpreted as responses to excessive use, the mechanisms responsible for anatomical changes associated with chronic pain are not so straightforward. The main aim of this paper is to explore the potential underlying cellular changes responsible for change in gross brain anatomy in individuals with chronic pain, in particular pain following nervous system damage. Determining the basis of these changes may provide a platform for development of targeted, personalized and ultimately more effective treatment regimens. |
| first_indexed | 2025-11-14T11:13:36Z |
| format | Journal Article |
| id | curtin-20.500.11937-79567 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | eng |
| last_indexed | 2025-11-14T11:13:36Z |
| publishDate | 2016 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-795672020-09-02T05:20:49Z How do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain? Henderson, L.A. Prieto, Flavia GABA astrocytes infra-slow oscillations neuropathic pain spinal trigeminal nucleus thalamocortical rhythm voxel-based morphometry Animals Brain Central Pattern Generators Chronic Pain Humans Neuralgia Pain Perception Since the advent of anatomical brain imaging analysis techniques, numerous reports have shown altered regional brain anatomy in individuals with various chronic pain conditions. While early reports of increased regional brain volumes in taxi drivers and pianists were simply interpreted as responses to excessive use, the mechanisms responsible for anatomical changes associated with chronic pain are not so straightforward. The main aim of this paper is to explore the potential underlying cellular changes responsible for change in gross brain anatomy in individuals with chronic pain, in particular pain following nervous system damage. Determining the basis of these changes may provide a platform for development of targeted, personalized and ultimately more effective treatment regimens. 2016 Journal Article http://hdl.handle.net/20.500.11937/79567 10.2217/pmt.15.67 eng restricted |
| spellingShingle | GABA astrocytes infra-slow oscillations neuropathic pain spinal trigeminal nucleus thalamocortical rhythm voxel-based morphometry Animals Brain Central Pattern Generators Chronic Pain Humans Neuralgia Pain Perception Henderson, L.A. Prieto, Flavia How do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain? |
| title | How do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain? |
| title_full | How do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain? |
| title_fullStr | How do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain? |
| title_full_unstemmed | How do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain? |
| title_short | How do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain? |
| title_sort | how do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain? |
| topic | GABA astrocytes infra-slow oscillations neuropathic pain spinal trigeminal nucleus thalamocortical rhythm voxel-based morphometry Animals Brain Central Pattern Generators Chronic Pain Humans Neuralgia Pain Perception |
| url | http://hdl.handle.net/20.500.11937/79567 |