Associations of physical activity or sedentary behaviour with pain sensitivity in young adults of the Raine Study
© 2019 Scandinavian Association for the Study of Pain. Published by Walter de Gruyter GmbH, Berlin/Boston. All rights reserved. There is high level evidence for physical activity (PA) improving outcomes in persistent pain disorders and one of the mechanisms proposed is the effect of exercise on cent...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
| Language: | English |
| Published: |
2019
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| Online Access: | http://hdl.handle.net/20.500.11937/79243 |
| _version_ | 1848764019838550016 |
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| author | Waller, Robert Smith, Anne Slater, Helen O'Sullivan, P. Beales, Darren McVeigh, Joanne Straker, Leon |
| author_facet | Waller, Robert Smith, Anne Slater, Helen O'Sullivan, P. Beales, Darren McVeigh, Joanne Straker, Leon |
| author_sort | Waller, Robert |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © 2019 Scandinavian Association for the Study of Pain. Published by Walter de Gruyter GmbH, Berlin/Boston. All rights reserved. There is high level evidence for physical activity (PA) improving outcomes in persistent pain disorders and one of the mechanisms proposed is the effect of exercise on central nociceptive modulation. Although laboratory studies and small field intervention studies suggest associations between physical activity and pain sensitivity, the association of objectively measured, habitual PA and sedentary behaviour (SB) with pain sensitivity requires further investigation. Current evidence suggests PA typically lowers pain sensitivity in people without pain or with single-site pain, whereas PA is frequently associated with an increase in pain sensitivity for those with multisite pain. The aim of this study was to explore the relationships of PA and SB with pain sensitivity measured by pressure pain thresholds and cold pain thresholds, considering the presence of single-site and multisite pain and controlling for potential confounders. Participants from the Western Australian Pregnancy Cohort (Raine) Study (n = 714) provided data at age 22-years. PA and SB were measured via accelerometry over a 7-day period. Pain sensitivity was measured using pressure pain threshold (4 sites) and cold pain threshold (wrist). Participants were grouped by number of pain areas into "No pain areas" (n = 438), "Single-site pain" (n = 113) and "Multisite pain" (n = 163) groups. The association of PA and SB variables with pain sensitivity was tested separately within each pain group by multivariable regression, adjusting for potential confounders. For those with "Single-site pain", higher levels (>13 min/day) of moderate-vigorous PA in ≥10 min bouts was associated with more pressure pain sensitivity (p = 0.035). Those with "Multisite pain" displayed increased cold pain sensitivity with greater amounts of vigorous PA (p = 0.011). Those with "No pain areas" displayed increased cold pain sensitivity with decreasing breaks from sedentary time (p = 0.046). This study was a comprehensive investigation of a community-based sample of young adults with "No pain areas", "Single-site pain" and "Multisite pain" and suggests some associations of measures of PA and SB with pain sensitivity. The findings suggest that the pattern of accumulation of PA and SB may be important to inform improved clinical management of musculoskeletal pain disorders. This study provides a baseline for follow-up studies using the Raine Study cohort. Future research should consider temporal influences of PA and SB on pain sensitivity, pain experience and consider using a broader range of pain sensitivity measures. |
| first_indexed | 2025-11-14T11:12:42Z |
| format | Journal Article |
| id | curtin-20.500.11937-79243 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | eng |
| last_indexed | 2025-11-14T11:12:42Z |
| publishDate | 2019 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-792432020-07-29T04:24:07Z Associations of physical activity or sedentary behaviour with pain sensitivity in young adults of the Raine Study Waller, Robert Smith, Anne Slater, Helen O'Sullivan, P. Beales, Darren McVeigh, Joanne Straker, Leon Raine Study accelerometry musculoskeletal pain sensitivity physical activity sedentary behaviour © 2019 Scandinavian Association for the Study of Pain. Published by Walter de Gruyter GmbH, Berlin/Boston. All rights reserved. There is high level evidence for physical activity (PA) improving outcomes in persistent pain disorders and one of the mechanisms proposed is the effect of exercise on central nociceptive modulation. Although laboratory studies and small field intervention studies suggest associations between physical activity and pain sensitivity, the association of objectively measured, habitual PA and sedentary behaviour (SB) with pain sensitivity requires further investigation. Current evidence suggests PA typically lowers pain sensitivity in people without pain or with single-site pain, whereas PA is frequently associated with an increase in pain sensitivity for those with multisite pain. The aim of this study was to explore the relationships of PA and SB with pain sensitivity measured by pressure pain thresholds and cold pain thresholds, considering the presence of single-site and multisite pain and controlling for potential confounders. Participants from the Western Australian Pregnancy Cohort (Raine) Study (n = 714) provided data at age 22-years. PA and SB were measured via accelerometry over a 7-day period. Pain sensitivity was measured using pressure pain threshold (4 sites) and cold pain threshold (wrist). Participants were grouped by number of pain areas into "No pain areas" (n = 438), "Single-site pain" (n = 113) and "Multisite pain" (n = 163) groups. The association of PA and SB variables with pain sensitivity was tested separately within each pain group by multivariable regression, adjusting for potential confounders. For those with "Single-site pain", higher levels (>13 min/day) of moderate-vigorous PA in ≥10 min bouts was associated with more pressure pain sensitivity (p = 0.035). Those with "Multisite pain" displayed increased cold pain sensitivity with greater amounts of vigorous PA (p = 0.011). Those with "No pain areas" displayed increased cold pain sensitivity with decreasing breaks from sedentary time (p = 0.046). This study was a comprehensive investigation of a community-based sample of young adults with "No pain areas", "Single-site pain" and "Multisite pain" and suggests some associations of measures of PA and SB with pain sensitivity. The findings suggest that the pattern of accumulation of PA and SB may be important to inform improved clinical management of musculoskeletal pain disorders. This study provides a baseline for follow-up studies using the Raine Study cohort. Future research should consider temporal influences of PA and SB on pain sensitivity, pain experience and consider using a broader range of pain sensitivity measures. 2019 Journal Article http://hdl.handle.net/20.500.11937/79243 10.1515/sjpain-2019-0038 eng restricted |
| spellingShingle | Raine Study accelerometry musculoskeletal pain sensitivity physical activity sedentary behaviour Waller, Robert Smith, Anne Slater, Helen O'Sullivan, P. Beales, Darren McVeigh, Joanne Straker, Leon Associations of physical activity or sedentary behaviour with pain sensitivity in young adults of the Raine Study |
| title | Associations of physical activity or sedentary behaviour with pain sensitivity in young adults of the Raine Study |
| title_full | Associations of physical activity or sedentary behaviour with pain sensitivity in young adults of the Raine Study |
| title_fullStr | Associations of physical activity or sedentary behaviour with pain sensitivity in young adults of the Raine Study |
| title_full_unstemmed | Associations of physical activity or sedentary behaviour with pain sensitivity in young adults of the Raine Study |
| title_short | Associations of physical activity or sedentary behaviour with pain sensitivity in young adults of the Raine Study |
| title_sort | associations of physical activity or sedentary behaviour with pain sensitivity in young adults of the raine study |
| topic | Raine Study accelerometry musculoskeletal pain sensitivity physical activity sedentary behaviour |
| url | http://hdl.handle.net/20.500.11937/79243 |