The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations.

The imprinted gene and parent-of-origin effect database (www.otago.ac.nz/IGC) consists of two sections. One section catalogues the current literature on imprinted genes in humans and animals. The second, and new, section catalogues current reports of parental origin of de novo mutations in humans al...

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Main Authors: Glaser, R.L., Ramsay, Josh, Morison, I.M.
Format: Journal Article
Language:English
Published: OXFORD UNIV PRESS 2006
Subjects:
Online Access:https://academic.oup.com/nar/article/34/suppl_1/D29/1133376
http://hdl.handle.net/20.500.11937/78107
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author Glaser, R.L.
Ramsay, Josh
Morison, I.M.
author_facet Glaser, R.L.
Ramsay, Josh
Morison, I.M.
author_sort Glaser, R.L.
building Curtin Institutional Repository
collection Online Access
description The imprinted gene and parent-of-origin effect database (www.otago.ac.nz/IGC) consists of two sections. One section catalogues the current literature on imprinted genes in humans and animals. The second, and new, section catalogues current reports of parental origin of de novo mutations in humans alone. The addition of a catalogue of de novo mutations that show a parent-of-origin effect expands the scope of the database and provides a useful tool for examining parental origin trends for different types of spontaneous mutations. This new section includes >1700 mutations, found in 59 different disorders. The 85 imprinted genes are described in 152 entries from several mammalian species. In addition, >300 other entries describe a range of reported parent-of-origin effects in animals.
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spelling curtin-20.500.11937-781072020-05-27T08:38:58Z The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations. Glaser, R.L. Ramsay, Josh Morison, I.M. Science & Technology Life Sciences & Biomedicine Biochemistry & Molecular Biology HUTCHINSON-GILFORD PROGERIA PATERNAL ORIGIN RETT-SYNDROME MECP2 MUTATIONS CHROMOSOME HUMANS The imprinted gene and parent-of-origin effect database (www.otago.ac.nz/IGC) consists of two sections. One section catalogues the current literature on imprinted genes in humans and animals. The second, and new, section catalogues current reports of parental origin of de novo mutations in humans alone. The addition of a catalogue of de novo mutations that show a parent-of-origin effect expands the scope of the database and provides a useful tool for examining parental origin trends for different types of spontaneous mutations. This new section includes >1700 mutations, found in 59 different disorders. The 85 imprinted genes are described in 152 entries from several mammalian species. In addition, >300 other entries describe a range of reported parent-of-origin effects in animals. 2006 Journal Article http://hdl.handle.net/20.500.11937/78107 10.1093/nar/gkj101 English https://academic.oup.com/nar/article/34/suppl_1/D29/1133376 OXFORD UNIV PRESS unknown
spellingShingle Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
HUTCHINSON-GILFORD PROGERIA
PATERNAL ORIGIN
RETT-SYNDROME
MECP2 MUTATIONS
CHROMOSOME
HUMANS
Glaser, R.L.
Ramsay, Josh
Morison, I.M.
The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations.
title The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations.
title_full The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations.
title_fullStr The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations.
title_full_unstemmed The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations.
title_short The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations.
title_sort imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations.
topic Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
HUTCHINSON-GILFORD PROGERIA
PATERNAL ORIGIN
RETT-SYNDROME
MECP2 MUTATIONS
CHROMOSOME
HUMANS
url https://academic.oup.com/nar/article/34/suppl_1/D29/1133376
http://hdl.handle.net/20.500.11937/78107