c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression

c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression

Treatment of muscle-invasive bladder cancer remains a major clinical challenge. Aberrant HGF/c-MET upregulation and activation is frequently observed in bladder cancer correlating with cancer progression and invasion. However, the mechanisms underlying HGF/c-MET-mediated invasion in bladder cancer r...

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Bibliographic Details
Main Authors: Sim, W.J., Iyengar, P.V., Lama, D., Lui, S.K.L., Ng, H.C., Haviv-Shapira, L., Domany, E., Kappei, D., Tan, T.Z., Saie, A., Jaynes, P.W., Verma, C.S., Kumar, A.P., Rouanne, M., Ha, H.K., Radulescu, C., ten Dijke, P., Eichhorn, Pieter, Thiery, J.P.
Format: Journal Article
Language:English
Published: NATURE PUBLISHING GROUP 2019
Subjects:
Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
EPITHELIAL-MESENCHYMAL TRANSITIONS
HEPATOCYTE GROWTH-FACTOR
MOLECULAR-DYNAMICS
UBIQUITIN LIGASE
CARCINOMA-CELLS
SCATTER FACTOR
WW DOMAINS
WEB SERVER
SRC
SMURF2
Online Access:http://hdl.handle.net/20.500.11937/77888

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