Genome-wide investigation of cellular targets and mode of action of the antifungal bacterial metabolite 2,4-diacetylphloroglucinol in Saccharomyces cerevisiae

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Genome-wide investigation of cellular targets and mode of action of the antifungal bacterial metabolite 2,4-diacetylphloroglucinol in Saccharomyces cerevisiae

Saccharomyces cerevisiae is a proven model to investigate the effects of small molecules and drugs on fungal and eukaryotic cells. In this study, the mode of action of an antifungal metabolite, 2,4-diacetylphloroglucinol (DAPG), was determined. Applying a combination of genetic and physiological app...

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Bibliographic Details
Main Authors:	Troppens, Danielle, Dmitriev, Ruslan, Papkovsky, Dmitri, O'Gara, Fergal, Morrissey, John
Format:	Journal Article
Published:	John Wiley & Sons 2013
Subjects:	respiration proton ionophore uncoupler CCCP genetic screen
Online Access:	http://hdl.handle.net/20.500.11937/7787

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