Objective moderate-to-vigorous physical activity in 1064 patients with COPD after stratification for gender, FEV1 and BMI

Objective moderate-to-vigorous physical activity in 1064 patients with COPD after stratification for gender, FEV1 and BMI

Background: Physical inactivity in COPD is associated with poor outcomes. Therefore, it is important to understand the determinants of moderate-to-vigorous physical activity (MVPA) in COPD. We aimed to assess the mean level of MVPA after stratification for gender, forced expiratory volume in the fir...

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Main Authors: Mesquita, R., Pitta, F., Donaire-Gonzalez, D., Deering, B., Patel, M., Mitchell, K., Alison, J., van Gestel, A., Zogg, S., Garcia-Aymerich, J., Hill, K., Romme, E., Kon, S., Albert, P., Waschki, B., Shrikrishna, D., Singh, S., Hopkinson, N., Miedinger, D., Jenkins, C., Polkey, M., Jenkins, S., Man, W., Clarenbach, C., Hernandes, N., Hillman, D., Furlanetto, K., McKeough, Z., Watts, S., Ng, L., Brooks, D., Eastwood, Peter, Sant'Anna, T., Meijer, K., Duerr, S., Kohler, M., Probst, V., Tal-Singer, R., Leuppi, J., Calverley, P., Smeenk, F., Yates, J., Costello, R., Goldstein, R., Magnussen, H., Wouters, E., ZuWallack, R., Watz, H., Spruit, M.
Format: Journal Article
Published: EUROPEAN RESPIRATORY SOC JOURNALS LTD 2013
Online Access:http://hdl.handle.net/20.500.11937/7786
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Summary:Background: Physical inactivity in COPD is associated with poor outcomes. Therefore, it is important to understand the determinants of moderate-to-vigorous physical activity (MVPA) in COPD. We aimed to assess the mean level of MVPA after stratification for gender, forced expiratory volume in the first second (FEV1) and body-mass index (BMI). Methods: In 1064 COPD subjects (716 men; age: 67±8 years; BMI: 27±6 kg• m-2; FEV1: 50±21 % predicted) from 14 centers, MVPA time was assessed using the SenseWear Armband activity monitor for ≥4 days. Gender, FEV1 and BMI were used for stratification. Results: In total, 6300 days with MVPA data were obtained, with a median (IQR) MVPA time of 27 (11-59) min• day-1. 47% of the subjects had a MVPA time ≥30 min• day-1. Men had a higher MVPA time than women (29 (12-63) versus 24 (9-52) min• day-1, respectively; p=0.002). Figure 1 presents the mean time in MVPA after stratification for GOLD classes and BMI in men (A) and women (B). Conclusions: This multicenter study showed that MVPA time generally is BMI-dependent (higher BMI results in lower MVPA) and GOLD-dependent (higher GOLD results in lower MVPA) in men and women with COPD.

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