Anti-diabetic action of Lupinus angustifolius seed proteins and peptides
Lupin seed proteins have been reported to exhibit hypoglycaemic action in animals and humans. This research focuses on exploring in-vitro anti-diabetic action of proteins extracted from Lupinus angustifolius seed. A novel insulin secretory mechanism of extract hydrolysate mediating through Gaq prote...
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| Format: | Thesis |
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Curtin University
2019
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| Online Access: | http://hdl.handle.net/20.500.11937/77246 |
| _version_ | 1848763834593968128 |
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| author | Tapadia, Mrunmai |
| author_facet | Tapadia, Mrunmai |
| author_sort | Tapadia, Mrunmai |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Lupin seed proteins have been reported to exhibit hypoglycaemic action in animals and humans. This research focuses on exploring in-vitro anti-diabetic action of proteins extracted from Lupinus angustifolius seed. A novel insulin secretory mechanism of extract hydrolysate mediating through Gaq protein signalling pathway in pancreatic ß-cells was established. γ-conglutin protein, a glucose modulating agent, was separated from the extract. Purified γ-conglutin was characterised and hydrolysed to evaluate its anti-diabetic properties in pancreatic ß-cells and myotubes. |
| first_indexed | 2025-11-14T11:09:46Z |
| format | Thesis |
| id | curtin-20.500.11937-77246 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:09:46Z |
| publishDate | 2019 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-772462025-01-15T04:07:57Z Anti-diabetic action of Lupinus angustifolius seed proteins and peptides Tapadia, Mrunmai Lupin seed proteins have been reported to exhibit hypoglycaemic action in animals and humans. This research focuses on exploring in-vitro anti-diabetic action of proteins extracted from Lupinus angustifolius seed. A novel insulin secretory mechanism of extract hydrolysate mediating through Gaq protein signalling pathway in pancreatic ß-cells was established. γ-conglutin protein, a glucose modulating agent, was separated from the extract. Purified γ-conglutin was characterised and hydrolysed to evaluate its anti-diabetic properties in pancreatic ß-cells and myotubes. 2019 Thesis http://hdl.handle.net/20.500.11937/77246 Curtin University fulltext |
| spellingShingle | Tapadia, Mrunmai Anti-diabetic action of Lupinus angustifolius seed proteins and peptides |
| title | Anti-diabetic action of Lupinus angustifolius seed proteins and peptides |
| title_full | Anti-diabetic action of Lupinus angustifolius seed proteins and peptides |
| title_fullStr | Anti-diabetic action of Lupinus angustifolius seed proteins and peptides |
| title_full_unstemmed | Anti-diabetic action of Lupinus angustifolius seed proteins and peptides |
| title_short | Anti-diabetic action of Lupinus angustifolius seed proteins and peptides |
| title_sort | anti-diabetic action of lupinus angustifolius seed proteins and peptides |
| url | http://hdl.handle.net/20.500.11937/77246 |