Homochirality in biomineral suprastructures induced by assembly of single-enantiomer amino acids from a nonracemic mixture
© 2019, The Author(s). Since Pasteur first successfully separated right-handed and left-handed tartrate crystals in 1848, the understanding of how homochirality is achieved from enantiomeric mixtures has long been incomplete. Here, we report on a chirality dominance effect where organized, three-dim...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal Article |
| Language: | English |
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NATURE PUBLISHING GROUP
2019
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| Subjects: | |
| Online Access: | http://purl.org/au-research/grants/arc/FT180100385 http://hdl.handle.net/20.500.11937/77066 |
| _version_ | 1848763811416244224 |
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| author | Jiang, W. Athanasiadou, D. Zhang, S. Demichelis, Raffaella Koziara, Katarzyna Raiteri, Paolo Nelea, V. Mi, W. Ma, J.A. Gale, Julian McKee, M.D. |
| author_facet | Jiang, W. Athanasiadou, D. Zhang, S. Demichelis, Raffaella Koziara, Katarzyna Raiteri, Paolo Nelea, V. Mi, W. Ma, J.A. Gale, Julian McKee, M.D. |
| author_sort | Jiang, W. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © 2019, The Author(s). Since Pasteur first successfully separated right-handed and left-handed tartrate crystals in 1848, the understanding of how homochirality is achieved from enantiomeric mixtures has long been incomplete. Here, we report on a chirality dominance effect where organized, three-dimensional homochiral suprastructures of the biomineral calcium carbonate (vaterite) can be induced from a mixed nonracemic amino acid system. Right-handed (counterclockwise) homochiral vaterite helicoids are induced when the amino acid l-Asp is in the majority, whereas left-handed (clockwise) homochiral morphology is induced when d-Asp is in the majority. Unexpectedly, the Asp that incorporates into the homochiral vaterite helicoids maintains the same enantiomer ratio as that of the initial growth solution, thus showing chirality transfer without chirality amplification. Changes in the degree of chirality of the vaterite helicoids are postulated to result from the extent of majority enantiomer assembly on the mineral surface. These mechanistic insights potentially have major implications for high-level advanced materials synthesis. |
| first_indexed | 2025-11-14T11:09:24Z |
| format | Journal Article |
| id | curtin-20.500.11937-77066 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T11:09:24Z |
| publishDate | 2019 |
| publisher | NATURE PUBLISHING GROUP |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-770662022-11-23T05:54:12Z Homochirality in biomineral suprastructures induced by assembly of single-enantiomer amino acids from a nonracemic mixture Jiang, W. Athanasiadou, D. Zhang, S. Demichelis, Raffaella Koziara, Katarzyna Raiteri, Paolo Nelea, V. Mi, W. Ma, J.A. Gale, Julian McKee, M.D. Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics ATOMIC-FORCE MICROSCOPY SYMMETRY-BREAKING CHIRAL SELECTION AMPLIFICATION INDUCTION PROTEINS DYNAMICS CALCITE SPECTROSCOPY ORGANIZATION © 2019, The Author(s). Since Pasteur first successfully separated right-handed and left-handed tartrate crystals in 1848, the understanding of how homochirality is achieved from enantiomeric mixtures has long been incomplete. Here, we report on a chirality dominance effect where organized, three-dimensional homochiral suprastructures of the biomineral calcium carbonate (vaterite) can be induced from a mixed nonracemic amino acid system. Right-handed (counterclockwise) homochiral vaterite helicoids are induced when the amino acid l-Asp is in the majority, whereas left-handed (clockwise) homochiral morphology is induced when d-Asp is in the majority. Unexpectedly, the Asp that incorporates into the homochiral vaterite helicoids maintains the same enantiomer ratio as that of the initial growth solution, thus showing chirality transfer without chirality amplification. Changes in the degree of chirality of the vaterite helicoids are postulated to result from the extent of majority enantiomer assembly on the mineral surface. These mechanistic insights potentially have major implications for high-level advanced materials synthesis. 2019 Journal Article http://hdl.handle.net/20.500.11937/77066 10.1038/s41467-019-10383-x English http://purl.org/au-research/grants/arc/FT180100385 http://purl.org/au-research/grants/arc/FL180100087 http://creativecommons.org/licenses/by/4.0/ NATURE PUBLISHING GROUP fulltext |
| spellingShingle | Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics ATOMIC-FORCE MICROSCOPY SYMMETRY-BREAKING CHIRAL SELECTION AMPLIFICATION INDUCTION PROTEINS DYNAMICS CALCITE SPECTROSCOPY ORGANIZATION Jiang, W. Athanasiadou, D. Zhang, S. Demichelis, Raffaella Koziara, Katarzyna Raiteri, Paolo Nelea, V. Mi, W. Ma, J.A. Gale, Julian McKee, M.D. Homochirality in biomineral suprastructures induced by assembly of single-enantiomer amino acids from a nonracemic mixture |
| title | Homochirality in biomineral suprastructures induced by assembly of single-enantiomer amino acids from a nonracemic mixture |
| title_full | Homochirality in biomineral suprastructures induced by assembly of single-enantiomer amino acids from a nonracemic mixture |
| title_fullStr | Homochirality in biomineral suprastructures induced by assembly of single-enantiomer amino acids from a nonracemic mixture |
| title_full_unstemmed | Homochirality in biomineral suprastructures induced by assembly of single-enantiomer amino acids from a nonracemic mixture |
| title_short | Homochirality in biomineral suprastructures induced by assembly of single-enantiomer amino acids from a nonracemic mixture |
| title_sort | homochirality in biomineral suprastructures induced by assembly of single-enantiomer amino acids from a nonracemic mixture |
| topic | Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics ATOMIC-FORCE MICROSCOPY SYMMETRY-BREAKING CHIRAL SELECTION AMPLIFICATION INDUCTION PROTEINS DYNAMICS CALCITE SPECTROSCOPY ORGANIZATION |
| url | http://purl.org/au-research/grants/arc/FT180100385 http://purl.org/au-research/grants/arc/FT180100385 http://hdl.handle.net/20.500.11937/77066 |