Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis.

Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis.

We aimed to determine whether myeloperoxidase (MPO) is the main peroxidase present in the airways of children with cystic fibrosis (CF) and to assess which oxidants it produces and whether they are associated with clinical features of CF. Children with CF (n=54) and without CF (n=16) underwent bronc...

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Bibliographic Details
Main Authors: Thomson, E., Brennan, S., Senthilmohan, R., Gangell, C., Chapman, A., Sly, P., Kettle, A., Balding, E., Berry, L., Carlin, J., Carzino, R., de Klerk, N., Douglas, T., Foo, C., Garratt, L., Hall, Graham, Harrison, J., Kicic, Anthony, Laing, I., Logie, K., Massie, J., Mott, L., Murray, C., Parsons, F., Pillarisetti, N., Poreddy, S., Ranganathan, S., Robertson, C., Robins-Browne, R., Robinson, P., Skoric, B., Stick, S., Sutanto, E., Williamson, E.
Format: Journal Article
Language:English
Published: 2010
Subjects:
Bronchoalveolar Lavage Fluid
Child
Child, Preschool
Cystic Fibrosis
Disease Progression
Female
Humans
Infant
Inflammation
Male
Neutrophils
Oxidation-Reduction
Peroxidase
Pseudomonas aeruginosa
Respiratory Tract Infections
Tyrosine
Online Access:http://hdl.handle.net/20.500.11937/76863

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