Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells
© 2019 American Chemical Society. As global biodiesel production increases, there are concerns over the potential health impact of exposure to the exhaust, particularly in regard to young children who are at high risk because of their continuing lung development. Using human airway epithelial cells...
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| Format: | Journal Article |
| Language: | English |
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AMER CHEMICAL SOC
2019
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| Online Access: | http://purl.org/au-research/grants/arc/DP170104346 http://hdl.handle.net/20.500.11937/76699 |
| _version_ | 1848763747828498432 |
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| author | Landwehr, K.R. Hillas, J. Mead-Hunter, Ryan O'Leary, R.A. Kicic, Anthony Mullins, Ben Larcombe, Alexander |
| author_facet | Landwehr, K.R. Hillas, J. Mead-Hunter, Ryan O'Leary, R.A. Kicic, Anthony Mullins, Ben Larcombe, Alexander |
| author_sort | Landwehr, K.R. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © 2019 American Chemical Society. As global biodiesel production increases, there are concerns over the potential health impact of exposure to the exhaust, particularly in regard to young children who are at high risk because of their continuing lung development. Using human airway epithelial cells obtained from young children, we compared the effects of exposure to exhaust generated by a diesel engine with Euro V/VI emission controls running on conventional diesel (ultra-low-sulfur mineral diesel, ULSD), soy biodiesel (B100), or a 20% blend of soy biodiesel with diesel (B20). The exhaust output of biodiesel was found to contain significantly more respiratory irritants, including NOx, CO, and CO2, and a larger overall particle mass. Exposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls and ULSD exhaust. These results have concerning implications for potential global health impacts, particularly for the pediatric population. |
| first_indexed | 2025-11-14T11:08:23Z |
| format | Journal Article |
| id | curtin-20.500.11937-76699 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T11:08:23Z |
| publishDate | 2019 |
| publisher | AMER CHEMICAL SOC |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-766992021-02-17T01:02:21Z Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells Landwehr, K.R. Hillas, J. Mead-Hunter, Ryan O'Leary, R.A. Kicic, Anthony Mullins, Ben Larcombe, Alexander Science & Technology Technology Life Sciences & Biomedicine Engineering, Environmental Environmental Sciences Engineering Environmental Sciences & Ecology CARBON-MONOXIDE NITROGEN-DIOXIDE 2ND-GENERATION BIODIESEL RESPIRATORY HEALTH EMISSIONS EXPOSURE POLLUTION PARTICLES ENGINE INHALATION © 2019 American Chemical Society. As global biodiesel production increases, there are concerns over the potential health impact of exposure to the exhaust, particularly in regard to young children who are at high risk because of their continuing lung development. Using human airway epithelial cells obtained from young children, we compared the effects of exposure to exhaust generated by a diesel engine with Euro V/VI emission controls running on conventional diesel (ultra-low-sulfur mineral diesel, ULSD), soy biodiesel (B100), or a 20% blend of soy biodiesel with diesel (B20). The exhaust output of biodiesel was found to contain significantly more respiratory irritants, including NOx, CO, and CO2, and a larger overall particle mass. Exposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls and ULSD exhaust. These results have concerning implications for potential global health impacts, particularly for the pediatric population. 2019 Journal Article http://hdl.handle.net/20.500.11937/76699 10.1021/acs.est.9b01671 English http://purl.org/au-research/grants/arc/DP170104346 AMER CHEMICAL SOC fulltext |
| spellingShingle | Science & Technology Technology Life Sciences & Biomedicine Engineering, Environmental Environmental Sciences Engineering Environmental Sciences & Ecology CARBON-MONOXIDE NITROGEN-DIOXIDE 2ND-GENERATION BIODIESEL RESPIRATORY HEALTH EMISSIONS EXPOSURE POLLUTION PARTICLES ENGINE INHALATION Landwehr, K.R. Hillas, J. Mead-Hunter, Ryan O'Leary, R.A. Kicic, Anthony Mullins, Ben Larcombe, Alexander Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells |
| title | Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells |
| title_full | Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells |
| title_fullStr | Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells |
| title_full_unstemmed | Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells |
| title_short | Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells |
| title_sort | soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells |
| topic | Science & Technology Technology Life Sciences & Biomedicine Engineering, Environmental Environmental Sciences Engineering Environmental Sciences & Ecology CARBON-MONOXIDE NITROGEN-DIOXIDE 2ND-GENERATION BIODIESEL RESPIRATORY HEALTH EMISSIONS EXPOSURE POLLUTION PARTICLES ENGINE INHALATION |
| url | http://purl.org/au-research/grants/arc/DP170104346 http://hdl.handle.net/20.500.11937/76699 |