Ceramide biosynthesis and metabolism in trophoblast syncytialization

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Ceramide biosynthesis and metabolism in trophoblast syncytialization

Sphingolipid mediators such as ceramide are pleiotropic regulators of cellular growth, differentiation and apoptosis. We investigated the role of ceramide biosynthesis, metabolism and actions in term human cytotrophoblasts syncytialized over 7 days in culture. Intracellular C16 ceramide levels incre...

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Bibliographic Details
Main Authors:	Singh, A., Dharmarajan, Arunasalam, Aye, I., Keelan, J.
Format:	Journal Article
Published:	Elsevier Ireland Ltd 2012
Subjects:	Placenta Acid sphingomyelinase Sphingolipid Cell fusion Ceramide kinase Ceramidase
Online Access:	http://hdl.handle.net/20.500.11937/7664

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