Modelling and Simulation of Chromatographic Processes for Whey Proteins

The research focuses on understanding implementation of modelling and simulation for ion exchange chromatography. A computational tool ExProSim:IC was developed in MATLAB2014b and literature based validation was performed for three thermodynamic models along with a mass transfer model. Furthermore,...

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Bibliographic Details
Main Author: Jadhav, Sanket H.
Format: Thesis
Published: Curtin University 2019
Online Access:http://hdl.handle.net/20.500.11937/76482
Description
Summary:The research focuses on understanding implementation of modelling and simulation for ion exchange chromatography. A computational tool ExProSim:IC was developed in MATLAB2014b and literature based validation was performed for three thermodynamic models along with a mass transfer model. Furthermore, detailed analysis of separation characteristics for major and minor whey protein standards, and crude whey protein concentrate was performed for experimental validation of the tool giving a better understanding of model parameters for simulation of chromatographic operations.