Formulation Development and Optimization for Transdermal Delivery of Peptide and Peptide Like Drugs
This research focused on transdermal penetration enhancement of peptides, peptide-like and lipophilic drugs by employing physical and chemical penetration enhancers. Three potential physical penetration enhancement tools, namely elongated microparticles, microneedles and Dermaroller®, significantly...
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| Format: | Thesis |
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Curtin University
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/74955 |
| _version_ | 1848763420650766336 |
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| author | Jhanker, Yeakuty Marzan |
| author_facet | Jhanker, Yeakuty Marzan |
| author_sort | Jhanker, Yeakuty Marzan |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | This research focused on transdermal penetration enhancement of peptides, peptide-like and lipophilic drugs by employing physical and chemical penetration enhancers. Three potential physical penetration enhancement tools, namely elongated microparticles, microneedles and Dermaroller®, significantly increased in vitro skin penetration and retention with further enhancement achieved by formulating with a chemical enhancer. We concluded that physical and chemical penetration enhancers are suitable tools for transdermal drug delivery. |
| first_indexed | 2025-11-14T11:03:11Z |
| format | Thesis |
| id | curtin-20.500.11937-74955 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:03:11Z |
| publishDate | 2018 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-749552021-03-26T03:10:08Z Formulation Development and Optimization for Transdermal Delivery of Peptide and Peptide Like Drugs Jhanker, Yeakuty Marzan This research focused on transdermal penetration enhancement of peptides, peptide-like and lipophilic drugs by employing physical and chemical penetration enhancers. Three potential physical penetration enhancement tools, namely elongated microparticles, microneedles and Dermaroller®, significantly increased in vitro skin penetration and retention with further enhancement achieved by formulating with a chemical enhancer. We concluded that physical and chemical penetration enhancers are suitable tools for transdermal drug delivery. 2018 Thesis http://hdl.handle.net/20.500.11937/74955 Curtin University fulltext |
| spellingShingle | Jhanker, Yeakuty Marzan Formulation Development and Optimization for Transdermal Delivery of Peptide and Peptide Like Drugs |
| title | Formulation Development and Optimization for Transdermal Delivery of Peptide and Peptide Like Drugs |
| title_full | Formulation Development and Optimization for Transdermal Delivery of Peptide and Peptide Like Drugs |
| title_fullStr | Formulation Development and Optimization for Transdermal Delivery of Peptide and Peptide Like Drugs |
| title_full_unstemmed | Formulation Development and Optimization for Transdermal Delivery of Peptide and Peptide Like Drugs |
| title_short | Formulation Development and Optimization for Transdermal Delivery of Peptide and Peptide Like Drugs |
| title_sort | formulation development and optimization for transdermal delivery of peptide and peptide like drugs |
| url | http://hdl.handle.net/20.500.11937/74955 |