gRASping the redox lever to modulate cancer cell fate signaling

QR Code

gRASping the redox lever to modulate cancer cell fate signaling

RAS proteins are critical regulators of signaling networks controlling diverse cellular functions such as cell proliferation and survival and its mutation are among the most powerful oncogenic drivers in human cancers. Despite intense efforts, direct RAS-targeting strategies remain elusive due to it...

Full description

Bibliographic Details
Main Authors:	Foo, C., Pervaiz, Shazib
Format:	Journal Article
Published:	Elsevier BV 2019
Online Access:	http://hdl.handle.net/20.500.11937/74805

Similar Items

Hippo circuitry and the redox modulation of hippo components in cancer cell fate decisions
by: Ashraf, A., et al.
Published: (2015)

Redox Dichotomy in Cell Fate Decision: Evasive Mechanism or Achilles Heel?
by: Pervaiz, Shazib
Published: (2018)

Redox regulation of cancer cell migration and invasion
by: Tochhawng, L., et al.
Published: (2013)

Mediation of triple-negative breast cancer cell fate via cellular redox and Wnt signalling
by: Pohl, Sebastian Öther-Gee
Published: (2018)

Breast Cancer: A Molecular and Redox Snapshot
by: Raman, D., et al.
Published: (2016)

Bcl-2: A prime regulator of mitochondrial redox metabolism in cancer cells
by: Low, I., et al.
Published: (2011)

Redox pioneer: Professor Barry Halliwell
by: Pervaiz, Shazib
Published: (2011)

Role of epigenetic modulation in cancer stem cell fate
by: Deshmukh, A., et al.
Published: (2017)

Na+/H+ exchanger 1 (NHE-1) redox-regulated gene and intracellular target for the redox control of cell death sensitivity
by: Akram, S., et al.
Published: (2011)

Crosstalk between Bcl-2 family and Ras family small GTPases: potential cell fate regulation?
by: Kang, J., et al.
Published: (2013)

Mitochondria: Redox metabolism and dysfunction
by: Kang, J., et al.
Published: (2012)

Redox regulation of p53, redox effectors regulated by p53: A subtle balance
by: Maillet, A., et al.
Published: (2012)

Redox inhibition of protein phosphatase PP2A: Potential implications in oncogenesis and its progression
by: Raman, D., et al.
Published: (2019)

Adenine nucleotide translocase family: Four isoforms for apoptosis modulation in cancer
by: Brenner, C., et al.
Published: (2011)

Cross talk between cellular redox state and the antiapoptotic protein Bcl-2
by: Pohl, Sebastian, et al.
Published: (2018)

Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells
by: Seah, S., et al.
Published: (2015)

Assessment of Oxidative Stress-Induced DNA Damage by Immunoflourescent Analysis of 8-OxodG
by: Lee, S., et al.
Published: (2011)

Repressing the activity of protein kinase CK2 releases the brakes on mitochondria-mediated apoptosis in cancer cells
by: Hanif, I., et al.
Published: (2011)

Designing uart by using gate-lever implementation
by: Iffah, Mohamed @ Mohamad Saim
Published: (2006)

Small Signaling Molecules and CO-Releasing Molecules (CORMs) for the Modulation of the Cellular Redox Metabolism
by: Simpson, Peter, et al.
Published: (2016)

Recent advances in apoptosis, mitochondria and drug resistance in cancer cells
by: Indran, I., et al.
Published: (2011)

Gene expression analysis of heat-shock proteins and redox regulators reveals combinatorial prognostic markers in carcinomas of the gastrointestinal tract
by: Pohl, S., et al.
Published: (2018)

Oxygen concentration modulates the differentiation of muscle stem cells toward myogenic and adipogenic fates
by: Redshaw, Zoe, et al.
Published: (2012)

Water lever measure and control using ultrasonic sensor
by: Abdul Hafiz, Mohd Idzhan
Published: (2016)

Mitochondrial redox modulation of NLRP3 inflammasome in differentiated THP-1 cells
by: Abas, Razif, et al.
Published: (2019)

Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer
by: Coombs, G., et al.
Published: (2012)

TMS over the supramarginal gyrus delays selection of appropriate grasp orientation during reaching and grasping tools for use
by: McDowell, Tomás, et al.
Published: (2018)

Key cell signaling pathways modulated by zerumbone: Role in the prevention and treatment of cancer
by: Prasannan, R., et al.
Published: (2012)

hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells
by: Indran, I., et al.
Published: (2011)

LeverAge: A European network to leverage the multi-age workforce
by: Marcus, J., et al.
Published: (2024)

Survivin and AURKA, key determinants of mitotic cell fate
by: Abdelkabir, Hana
Published: (2024)

Physical Activity and Redox Balance in the Elderly: Signal Transduction Mechanisms
by: Galli, Daniela, et al.
Published: (2021)

Circuit breakers as market stability levers: a survey of research, praxis, and challenges
by: Sifat, Imtiaz Mohammad, et al.
Published: (2019)

Circuit breakers as market stability levers: a survey of research, praxis, and challenges
by: Sifat, Imtiaz Mohammad, et al.
Published: (2018)

Grasp on next generation security operation centre (NGSOC):
by: Dun, Yau Ti, et al.
Published: (2021)

The identification and control of a finger exoskeleton for grasping rehabilitation
by: Zahari, Taha, et al.
Published: (2018)

ROS, autophagy, mitochondria and cancer: Ras, the hidden master?
by: Bellot, G., et al.
Published: (2013)

Synthetic Lethality of a Novel Small Molecule Against Mutant KRAS-Expressing Cancer Cells Involves AKT-Dependent ROS Production
by: Iskandar, K., et al.
Published: (2016)

Transcriptional and epigenetic control of cell fate decisions in early embryos
by: Alberio, Ramiro
Published: (2017)

High throughput screening for discovery of materials that control stem cell fate
by: Patel, Asha K., et al.
Published: (2016)