Redox inhibition of protein phosphatase PP2A: Potential implications in oncogenesis and its progression

QR Code

Redox inhibition of protein phosphatase PP2A: Potential implications in oncogenesis and its progression

Cellular processes are dictated by the active signaling of proteins relaying messages to regulate cell proliferation, apoptosis, signal transduction and cell communications. An intricate web of protein kinases and phosphatases are critical to the proper transmission of signals across such cascades....

Full description

Bibliographic Details
Main Authors:	Raman, D., Pervaiz, Shazib
Format:	Journal Article
Published:	Elsevier BV 2019
Online Access:	http://hdl.handle.net/20.500.11937/74776

Similar Items

Redox pioneer: Professor Barry Halliwell
by: Pervaiz, Shazib
Published: (2011)

Cross talk between cellular redox state and the antiapoptotic protein Bcl-2
by: Pohl, Sebastian, et al.
Published: (2018)

Mitochondria: Redox metabolism and dysfunction
by: Kang, J., et al.
Published: (2012)

Redox regulation of p53, redox effectors regulated by p53: A subtle balance
by: Maillet, A., et al.
Published: (2012)

Breast Cancer: A Molecular and Redox Snapshot
by: Raman, D., et al.
Published: (2016)

Redox Dichotomy in Cell Fate Decision: Evasive Mechanism or Achilles Heel?
by: Pervaiz, Shazib
Published: (2018)

Na+/H+ exchanger 1 (NHE-1) redox-regulated gene and intracellular target for the redox control of cell death sensitivity
by: Akram, S., et al.
Published: (2011)

Bcl-2: A prime regulator of mitochondrial redox metabolism in cancer cells
by: Low, I., et al.
Published: (2011)

Inflammatory role of transforming growth factor beta-1 (TGF-β1) in multistep progression of gastric oncogenesis: an immunohistochemical study
by: Ismail, Ahmad Zharif, et al.
Published: (2015)

gRASping the redox lever to modulate cancer cell fate signaling
by: Foo, C., et al.
Published: (2019)

Gene expression analysis of heat-shock proteins and redox regulators reveals combinatorial prognostic markers in carcinomas of the gastrointestinal tract
by: Pohl, S., et al.
Published: (2018)

Hippo circuitry and the redox modulation of hippo components in cancer cell fate decisions
by: Ashraf, A., et al.
Published: (2015)

Redox regulation of cancer cell migration and invasion
by: Tochhawng, L., et al.
Published: (2013)

Ser70 phosphorylation of Bcl-2 by selective tyrosine nitration of PP2A-B56 d stabilizes its antiapoptotic activity
by: Low, I., et al.
Published: (2014)

Repressing the activity of protein kinase CK2 releases the brakes on mitochondria-mediated apoptosis in cancer cells
by: Hanif, I., et al.
Published: (2011)

The interactions of metal cations and oxyanions with protein tyrosine phosphatase 1B
by: Singh, Karam, et al.
Published: (2017)

Virtual Screening Of Protein Tyrosine Phosphatase 1b In Search For Natural Products With Potential Activity Againts Diabetes Mellitus Type 2
by: Ho, Yueng Hsing
Published: (2018)

Chimeric design, synthesis, and biological assays of a new nonpeptide insulin-mimetic vanadium compound to inhibit protein tyrosine phosphatase 1B
by: Thomas, Scior, et al.
Published: (2010)

Crosstalk between Bcl-2 family and Ras family small GTPases: potential cell fate regulation?
by: Kang, J., et al.
Published: (2013)

Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1
by: Rajendran, P., et al.
Published: (2012)

Isolation of a potential anticancer agent with protein phosphatase inhibitory activity from soil-derived Penicillium sp. strain H9318
by: Ooi, S. C., et al.
Published: (2016)

Saliva acid phosphatases: genetic studies
by: Tan, Soon Guan, et al.
Published: (1976)

hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells
by: Indran, I., et al.
Published: (2011)

Could protein phosphatase 2A and glycogen synthase kinase-3 beta be targeted by natural compounds to ameliorate Alzheimer’s pathologies?
by: Manoharan, Sushmitaa Dhevii, et al.
Published: (2024)

Alkaline Phosphatase Purification from Bacillus megaterium
by: Hussin, Huszalina, et al.
Published: (2012)

The role of redox proteins in the radiotherapeutic response of breast cancer
by: Abdullah, Nurul Akmaryanti
Published: (2019)

A redox protein immobilization on multiporous nanofibers of SnO2 for improvement of sensing
by: A. K. M., Kafi, et al.
Published: (2018)

KIF1Bß increases ROS to mediate apoptosis and reinforces its protein expression through O2− in a positive feedback mechanism in neuroblastoma
by: Angelina, C., et al.
Published: (2017)

A unique protein phosphatase with kelch-like domains (PPKL) in plasmodium modulates ookinete differentiation, motility and invasion
by: Guttery, David S., et al.
Published: (2012)

Fabrication of 3-dimensional Cross-linked Redox Protein/Nanomaterials
by: A. K. M., Kafi, et al.
Published: (2015)

Redox equilibria of iron oxides in aqueous-based magnetite dispersions:Effect of pH and redox potential
by: Pang, S.C., et al.
Published: (2007)

The Effect of Redox Potential on the Leaching of Chalcopyrite in Chloride Media
by: Yoo, K., et al.
Published: (2007)

A RNA interference screen identifies the protein phosphatase 2A subunit PR55γ as a stress-sensitive inhibitor of c-SRC
by: Eichhorn, Pieter, et al.
Published: (2007)

Conference roundup MAC 2011
by: Pervaiz, Shazib
Published: (2013)

Enhanced direct electron transfer of redox protein based on multiporous SnO2 nanofiber-carbon nanotube nanocomposite and its application in biosensing
by: Alim, Samiul, et al.
Published: (2018)

The anti-oxidant and pro-oxidant dichotomy of Bcl-2.
by: Yee, Y., et al.
Published: (2016)

Saliva acid phosphatases in Malaysians: report of a new variant
by: Tan, Soon Guan, et al.
Published: (1979)

Isolated disproportionately raised alkaline phosphatase: should we worry?
by: Lee, Yee Lin, et al.
Published: (2020)

Small molecule sensitization to TRAIL is mediated via nuclear localization, phosphorylation and inhibition of chaperone activity of Hsp27
by: Mellier, G., et al.
Published: (2013)

Mitochondrial ROS and involvement of Bcl-2 as a mitochondrial ROS regulator
by: Chong, S., et al.
Published: (2014)