Diagnosis of asbestos-related lung diseases

Introduction: The diagnosis of lung disease in asbestos-exposed individuals is a process that not only requires a detailed occupational and tobacco smoking history, but the correlation with physical signs, appropriate imaging, detailed lung function assessment and histology/cytology when required. W...

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Main Authors: Harris, E., Musk, A., de Klerk, N., Reid, Alison, Franklin, P., Brims, Fraser
Format: Journal Article
Published: 2019
Online Access:http://hdl.handle.net/20.500.11937/74194
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author Harris, E.
Musk, A.
de Klerk, N.
Reid, Alison
Franklin, P.
Brims, Fraser
author_facet Harris, E.
Musk, A.
de Klerk, N.
Reid, Alison
Franklin, P.
Brims, Fraser
author_sort Harris, E.
building Curtin Institutional Repository
collection Online Access
description Introduction: The diagnosis of lung disease in asbestos-exposed individuals is a process that not only requires a detailed occupational and tobacco smoking history, but the correlation with physical signs, appropriate imaging, detailed lung function assessment and histology/cytology when required. Worldwide, the total quantity of asbestos mined is static, having decreased dramatically in developed countries but increased in countries where there is no restriction on mining: for example, Russia, China, Brazil, and Kazakhstan. The predominant diagnostic challenge in most cases of possible asbestos-related disease is the significant interval between exposure and development of the disease. Also challenging is the estimation of an individual's risk of disease, not least because asbestos-induced malignancy can be rapidly fatal, and, in the case of lung cancer, early detection can lead to treatment with curative intent. Areas covered: Discussion of quantitative asbestos exposure estimation and risk assessment, selection of the most appropriate imaging modality and frequency of imaging. Expert commentary: Consideration of the future for asbestos-related lung disease includes screening those at highest risk particularly in relation to ongoing mining operations and the management of in-situ asbestos. In the future, screening programs designed with estimation of risk of malignancy, based on quantitative estimates of asbestos exposure, and smoking history are indicated.
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spelling curtin-20.500.11937-741942019-08-01T07:37:01Z Diagnosis of asbestos-related lung diseases Harris, E. Musk, A. de Klerk, N. Reid, Alison Franklin, P. Brims, Fraser Introduction: The diagnosis of lung disease in asbestos-exposed individuals is a process that not only requires a detailed occupational and tobacco smoking history, but the correlation with physical signs, appropriate imaging, detailed lung function assessment and histology/cytology when required. Worldwide, the total quantity of asbestos mined is static, having decreased dramatically in developed countries but increased in countries where there is no restriction on mining: for example, Russia, China, Brazil, and Kazakhstan. The predominant diagnostic challenge in most cases of possible asbestos-related disease is the significant interval between exposure and development of the disease. Also challenging is the estimation of an individual's risk of disease, not least because asbestos-induced malignancy can be rapidly fatal, and, in the case of lung cancer, early detection can lead to treatment with curative intent. Areas covered: Discussion of quantitative asbestos exposure estimation and risk assessment, selection of the most appropriate imaging modality and frequency of imaging. Expert commentary: Consideration of the future for asbestos-related lung disease includes screening those at highest risk particularly in relation to ongoing mining operations and the management of in-situ asbestos. In the future, screening programs designed with estimation of risk of malignancy, based on quantitative estimates of asbestos exposure, and smoking history are indicated. 2019 Journal Article http://hdl.handle.net/20.500.11937/74194 10.1080/17476348.2019.1568875 restricted
spellingShingle Harris, E.
Musk, A.
de Klerk, N.
Reid, Alison
Franklin, P.
Brims, Fraser
Diagnosis of asbestos-related lung diseases
title Diagnosis of asbestos-related lung diseases
title_full Diagnosis of asbestos-related lung diseases
title_fullStr Diagnosis of asbestos-related lung diseases
title_full_unstemmed Diagnosis of asbestos-related lung diseases
title_short Diagnosis of asbestos-related lung diseases
title_sort diagnosis of asbestos-related lung diseases
url http://hdl.handle.net/20.500.11937/74194