Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents

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Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents

The discovery of a new series of compounds that are potent, selective 5-HT2C receptor agonists is described herein as we continue our efforts to optimize the 2-phenylcyclopropylmethylamine scaffold. Modifications focused on the alkoxyl substituent present on the aromatic ring led to the identificati...

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Bibliographic Details
Main Authors:	Cheng, J., Giguère, P., Onajole, O., Lv, W., Gaisin, A., Gunosewoyo, Hendra, Schmerberg, C., Pogorelov, V., Rodriguiz, R., Vistoli, G., Wetsel, W., Roth, B., Kozikowski, A.
Format:	Journal Article
Published:	American Chemical Society 2015
Online Access:	http://hdl.handle.net/20.500.11937/7396

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