Clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization
Aims: The aim was to describe outcomes among patients with stable coronary artery disease (CAD) with or without a history of myocardial revascularization in a large contemporary cohort. Methods and results: Patients with stable CAD were selected from the Reduction of Atherothrombosis for Continued H...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
2016
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| Online Access: | http://hdl.handle.net/20.500.11937/73630 |
| _version_ | 1848763051882315776 |
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| author | Elbez, Y. Cheong, A. Fassa, A. Cohen, E. Reid, Christopher Babarskiene, R. Bhatt, D. Steg, P. |
| author_facet | Elbez, Y. Cheong, A. Fassa, A. Cohen, E. Reid, Christopher Babarskiene, R. Bhatt, D. Steg, P. |
| author_sort | Elbez, Y. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Aims: The aim was to describe outcomes among patients with stable coronary artery disease (CAD) with or without a history of myocardial revascularization in a large contemporary cohort. Methods and results: Patients with stable CAD were selected from the Reduction of Atherothrombosis for Continued Health (REACH) registry. The cohort was divided into patients with (n = 25 583) and without (n = 13 133) a history of myocardial revascularization. Crude outcomes were described according to the use and type of revascularization: percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG). The primary outcome was cardiovascular (CV) death. At baseline, the non-revascularized group was older and had more CV risk factors. At 36-month median followup, previous revascularization was associated with a lower risk of CV death [crude incidence rate (CIR): 6.82 vs. 9.08%, hazard ratio (HR) 0.73 [95% confidence interval (CI) 0.66.0.80]; P < 0.01]. This association was seen for patients with a history of PCI (CIR 5.78 vs. 8.88%, HR 0.64 [0.58.0.71]; P = 0.01), but not with CABG (HR 1.26 [1.14.1.49]; P < 0.01), and was consistent regardless of prior MI and the timing of prior revascularization. Conclusion: Among patients with stable CAD, a history of myocardial revascularization was associated with lower CV mortality, particularly when PCI was the mode of revascularization. Coronary artery disease patients managed non-invasively represent a high-risk group. |
| first_indexed | 2025-11-14T10:57:19Z |
| format | Journal Article |
| id | curtin-20.500.11937-73630 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:57:19Z |
| publishDate | 2016 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-736302019-07-16T03:50:49Z Clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization Elbez, Y. Cheong, A. Fassa, A. Cohen, E. Reid, Christopher Babarskiene, R. Bhatt, D. Steg, P. Aims: The aim was to describe outcomes among patients with stable coronary artery disease (CAD) with or without a history of myocardial revascularization in a large contemporary cohort. Methods and results: Patients with stable CAD were selected from the Reduction of Atherothrombosis for Continued Health (REACH) registry. The cohort was divided into patients with (n = 25 583) and without (n = 13 133) a history of myocardial revascularization. Crude outcomes were described according to the use and type of revascularization: percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG). The primary outcome was cardiovascular (CV) death. At baseline, the non-revascularized group was older and had more CV risk factors. At 36-month median followup, previous revascularization was associated with a lower risk of CV death [crude incidence rate (CIR): 6.82 vs. 9.08%, hazard ratio (HR) 0.73 [95% confidence interval (CI) 0.66.0.80]; P < 0.01]. This association was seen for patients with a history of PCI (CIR 5.78 vs. 8.88%, HR 0.64 [0.58.0.71]; P = 0.01), but not with CABG (HR 1.26 [1.14.1.49]; P < 0.01), and was consistent regardless of prior MI and the timing of prior revascularization. Conclusion: Among patients with stable CAD, a history of myocardial revascularization was associated with lower CV mortality, particularly when PCI was the mode of revascularization. Coronary artery disease patients managed non-invasively represent a high-risk group. 2016 Journal Article http://hdl.handle.net/20.500.11937/73630 10.1093/ehjqcco/qcv017 restricted |
| spellingShingle | Elbez, Y. Cheong, A. Fassa, A. Cohen, E. Reid, Christopher Babarskiene, R. Bhatt, D. Steg, P. Clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization |
| title | Clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization |
| title_full | Clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization |
| title_fullStr | Clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization |
| title_full_unstemmed | Clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization |
| title_short | Clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization |
| title_sort | clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization |
| url | http://hdl.handle.net/20.500.11937/73630 |