Evaluation of Novel Resveratrol Conjugate and Nanoparticle Formulations for Enhanced Anticancer Activity
Resveratrol is known to undergo rapid metabolism and degradation in vivo. The aim of this project is to synthesise polymeric resveratrol conjugates for formulation into nanoparticles for enhanced anticancer treatment by decreasing the metabolism and degradation rate of resveratrol in vivo. Conjugate...
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| Format: | Thesis |
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Curtin University
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/73581 |
| _version_ | 1848762315787206656 |
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| author | Yee, Yan Jing |
| author_facet | Yee, Yan Jing |
| author_sort | Yee, Yan Jing |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Resveratrol is known to undergo rapid metabolism and degradation in vivo. The aim of this project is to synthesise polymeric resveratrol conjugates for formulation into nanoparticles for enhanced anticancer treatment by decreasing the metabolism and degradation rate of resveratrol in vivo. Conjugated resveratrol nanoparticles were found to suppress tumour growth in vivo in a melanoma mouse model although in vitro data shows lesser anti-proliferative effect than resveratrol alone. |
| first_indexed | 2025-11-14T10:45:37Z |
| format | Thesis |
| id | curtin-20.500.11937-73581 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:45:37Z |
| publishDate | 2018 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-735812022-01-31T01:13:17Z Evaluation of Novel Resveratrol Conjugate and Nanoparticle Formulations for Enhanced Anticancer Activity Yee, Yan Jing Resveratrol is known to undergo rapid metabolism and degradation in vivo. The aim of this project is to synthesise polymeric resveratrol conjugates for formulation into nanoparticles for enhanced anticancer treatment by decreasing the metabolism and degradation rate of resveratrol in vivo. Conjugated resveratrol nanoparticles were found to suppress tumour growth in vivo in a melanoma mouse model although in vitro data shows lesser anti-proliferative effect than resveratrol alone. 2018 Thesis http://hdl.handle.net/20.500.11937/73581 Curtin University fulltext |
| spellingShingle | Yee, Yan Jing Evaluation of Novel Resveratrol Conjugate and Nanoparticle Formulations for Enhanced Anticancer Activity |
| title | Evaluation of Novel Resveratrol Conjugate and Nanoparticle Formulations for Enhanced Anticancer Activity |
| title_full | Evaluation of Novel Resveratrol Conjugate and Nanoparticle Formulations for Enhanced Anticancer Activity |
| title_fullStr | Evaluation of Novel Resveratrol Conjugate and Nanoparticle Formulations for Enhanced Anticancer Activity |
| title_full_unstemmed | Evaluation of Novel Resveratrol Conjugate and Nanoparticle Formulations for Enhanced Anticancer Activity |
| title_short | Evaluation of Novel Resveratrol Conjugate and Nanoparticle Formulations for Enhanced Anticancer Activity |
| title_sort | evaluation of novel resveratrol conjugate and nanoparticle formulations for enhanced anticancer activity |
| url | http://hdl.handle.net/20.500.11937/73581 |