Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies
© 2016 Society for the Study of Addiction Aims: To test if polysubstance use profiles and drug-related outcomes differ between those receiving and not receiving opioid substitution therapies (OST) among people who inject drugs (PWID). Design: An annual cross-sectional, sentinel sample of PWID across...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
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Wiley-Blackwell Publishing Ltd.
2016
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| Online Access: | http://hdl.handle.net/20.500.11937/73175 |
| _version_ | 1848762944217677824 |
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| author | Betts, K. Chan, G. McIlwraith, F. Dietze, P. Whittaker, E. Burns, L. Alati, Rosa |
| author_facet | Betts, K. Chan, G. McIlwraith, F. Dietze, P. Whittaker, E. Burns, L. Alati, Rosa |
| author_sort | Betts, K. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © 2016 Society for the Study of Addiction Aims: To test if polysubstance use profiles and drug-related outcomes differ between those receiving and not receiving opioid substitution therapies (OST) among people who inject drugs (PWID). Design: An annual cross-sectional, sentinel sample of PWID across Australia. Setting: Data came from 3 years (2011–13) of the Illicit Drug Reporting System (IDRS). Participants: A total of 2673 participants who injected drugs from the combined national IDRS samples of 2011 (n = 868), 2012 (n = 922) and 2013 (n = 883). Measurements: Latent class analysis (LCA) was used to summarize participants' self-reported use of 18 types of substances, with the resulting polysubstance use profiles then associated with participant experience of a number of drug-related outcomes. Findings: Polysubstance use profiles exhibiting a broad range of substance use were generally at increased risk of negative drug-related outcomes, whether or not participants were receiving OST, including thrombosis among OST receivers [odds ratio (OR) = 2.13, 95% confidence intervals (CI) = 1.09–4.17], injecting with used needles among OST receivers and non-receivers, respectively (OR = 2.78, 95% CI = 1.50–5.13; OR = 2.15, 95% CI = 1.34–3.45) and violent criminal offences among OST receivers and non-receivers, respectively (OR =2.30, 95% CI = 1.16–4.58; OR = 1.87, 95% CI = 1.14–3.07). An important exception was non-fatal overdose which was related specifically to a class of PWID who were not receiving OST and used morphine frequently (OR = 1.83, 95% CI = 1.06–3.17). Conclusion: Regardless of opioid substitution therapies usage, people who inject drugs who use a broad-range of substances experience greater levels of injecting-related injuries and poorer health outcomes and are more likely to engage in criminal activity than other groups of people who inject drugs. |
| first_indexed | 2025-11-14T10:55:36Z |
| format | Journal Article |
| id | curtin-20.500.11937-73175 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:55:36Z |
| publishDate | 2016 |
| publisher | Wiley-Blackwell Publishing Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-731752018-12-13T09:35:22Z Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies Betts, K. Chan, G. McIlwraith, F. Dietze, P. Whittaker, E. Burns, L. Alati, Rosa © 2016 Society for the Study of Addiction Aims: To test if polysubstance use profiles and drug-related outcomes differ between those receiving and not receiving opioid substitution therapies (OST) among people who inject drugs (PWID). Design: An annual cross-sectional, sentinel sample of PWID across Australia. Setting: Data came from 3 years (2011–13) of the Illicit Drug Reporting System (IDRS). Participants: A total of 2673 participants who injected drugs from the combined national IDRS samples of 2011 (n = 868), 2012 (n = 922) and 2013 (n = 883). Measurements: Latent class analysis (LCA) was used to summarize participants' self-reported use of 18 types of substances, with the resulting polysubstance use profiles then associated with participant experience of a number of drug-related outcomes. Findings: Polysubstance use profiles exhibiting a broad range of substance use were generally at increased risk of negative drug-related outcomes, whether or not participants were receiving OST, including thrombosis among OST receivers [odds ratio (OR) = 2.13, 95% confidence intervals (CI) = 1.09–4.17], injecting with used needles among OST receivers and non-receivers, respectively (OR = 2.78, 95% CI = 1.50–5.13; OR = 2.15, 95% CI = 1.34–3.45) and violent criminal offences among OST receivers and non-receivers, respectively (OR =2.30, 95% CI = 1.16–4.58; OR = 1.87, 95% CI = 1.14–3.07). An important exception was non-fatal overdose which was related specifically to a class of PWID who were not receiving OST and used morphine frequently (OR = 1.83, 95% CI = 1.06–3.17). Conclusion: Regardless of opioid substitution therapies usage, people who inject drugs who use a broad-range of substances experience greater levels of injecting-related injuries and poorer health outcomes and are more likely to engage in criminal activity than other groups of people who inject drugs. 2016 Journal Article http://hdl.handle.net/20.500.11937/73175 10.1111/add.13339 Wiley-Blackwell Publishing Ltd. restricted |
| spellingShingle | Betts, K. Chan, G. McIlwraith, F. Dietze, P. Whittaker, E. Burns, L. Alati, Rosa Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies |
| title | Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies |
| title_full | Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies |
| title_fullStr | Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies |
| title_full_unstemmed | Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies |
| title_short | Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies |
| title_sort | differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies |
| url | http://hdl.handle.net/20.500.11937/73175 |