A systematic review and meta-analysis of the association between unintended pregnancy and perinatal depression

© 2015 Elsevier B.V. All rights reserved. Background There is a growing interest in exploring maternal mental health effects of unintended pregnancies carried to term. However, the evidence base from a small number of available studies is characterised by considerable variability, inconsistency and...

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Main Authors: Abajobir, A., Maravilla, J., Alati, Rosa, Najman, J.
Format: Journal Article
Published: Elsevier BV 2016
Online Access:http://hdl.handle.net/20.500.11937/73150
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author Abajobir, A.
Maravilla, J.
Alati, Rosa
Najman, J.
author_facet Abajobir, A.
Maravilla, J.
Alati, Rosa
Najman, J.
author_sort Abajobir, A.
building Curtin Institutional Repository
collection Online Access
description © 2015 Elsevier B.V. All rights reserved. Background There is a growing interest in exploring maternal mental health effects of unintended pregnancies carried to term. However, the evidence base from a small number of available studies is characterised by considerable variability, inconsistency and inconclusive findings. We present a systematic review and meta-analysis of all available studies on unintended pregnancy as these are related to maternal depression. Methods Using PRISMA guideline, we systematically reviewed and meta-analysed studies reporting an association between unintended pregnancy and maternal depression from PubMed, EMBASE, PsychINFO and Google Scholar. We used a priori set criteria and included details of quality and magnitude of effect sizes. Sample sizes, adjusted odds ratios and standard errors were extracted. Random effects were used to calculate pooled estimates in Stata 13. Cochran's Q, I2 and meta-bias statistics assessed heterogeneity and publication bias of included studies. Results Meta-bias and funnel plot of inverse variance detected no publication bias. Overall prevalence of maternal depression in unintended pregnancy was 21%. Unintended pregnancy was significantly associated with maternal depression. Despite statistically significant heterogeneities of included studies, sub-group analyses revealed positive and significant associations by types of unintended pregnancies, timing of measurements with respect to pregnancy and childbirth, study designs and settings. Conclusions The prevalence of perinatal depression is two-fold in women with unintended pregnancy. Perinatal care settings may screen pregnancy intention and depression of women backed by integrating family planning and mental health services.
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spelling curtin-20.500.11937-731502018-12-13T09:35:32Z A systematic review and meta-analysis of the association between unintended pregnancy and perinatal depression Abajobir, A. Maravilla, J. Alati, Rosa Najman, J. © 2015 Elsevier B.V. All rights reserved. Background There is a growing interest in exploring maternal mental health effects of unintended pregnancies carried to term. However, the evidence base from a small number of available studies is characterised by considerable variability, inconsistency and inconclusive findings. We present a systematic review and meta-analysis of all available studies on unintended pregnancy as these are related to maternal depression. Methods Using PRISMA guideline, we systematically reviewed and meta-analysed studies reporting an association between unintended pregnancy and maternal depression from PubMed, EMBASE, PsychINFO and Google Scholar. We used a priori set criteria and included details of quality and magnitude of effect sizes. Sample sizes, adjusted odds ratios and standard errors were extracted. Random effects were used to calculate pooled estimates in Stata 13. Cochran's Q, I2 and meta-bias statistics assessed heterogeneity and publication bias of included studies. Results Meta-bias and funnel plot of inverse variance detected no publication bias. Overall prevalence of maternal depression in unintended pregnancy was 21%. Unintended pregnancy was significantly associated with maternal depression. Despite statistically significant heterogeneities of included studies, sub-group analyses revealed positive and significant associations by types of unintended pregnancies, timing of measurements with respect to pregnancy and childbirth, study designs and settings. Conclusions The prevalence of perinatal depression is two-fold in women with unintended pregnancy. Perinatal care settings may screen pregnancy intention and depression of women backed by integrating family planning and mental health services. 2016 Journal Article http://hdl.handle.net/20.500.11937/73150 10.1016/j.jad.2015.12.008 Elsevier BV restricted
spellingShingle Abajobir, A.
Maravilla, J.
Alati, Rosa
Najman, J.
A systematic review and meta-analysis of the association between unintended pregnancy and perinatal depression
title A systematic review and meta-analysis of the association between unintended pregnancy and perinatal depression
title_full A systematic review and meta-analysis of the association between unintended pregnancy and perinatal depression
title_fullStr A systematic review and meta-analysis of the association between unintended pregnancy and perinatal depression
title_full_unstemmed A systematic review and meta-analysis of the association between unintended pregnancy and perinatal depression
title_short A systematic review and meta-analysis of the association between unintended pregnancy and perinatal depression
title_sort systematic review and meta-analysis of the association between unintended pregnancy and perinatal depression
url http://hdl.handle.net/20.500.11937/73150