Production of Lactobacilli Proteinases for the Manufacture of Bioactive Peptides: Part I-Upstream Processes

This chapter focuses on the metabolism of genus Lactobacillus, with emphasis on the proteolytic potential of the well-known species in order to highlight their potential use in the production of bioactive peptides. Fermentation activities for most of the literature references used in this chapter we...

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Main Authors: Agyei, D., Potumarthi, R., Danquah, Michael
Format: Book Chapter
Published: 2013
Online Access:http://hdl.handle.net/20.500.11937/7313
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author Agyei, D.
Potumarthi, R.
Danquah, Michael
author_facet Agyei, D.
Potumarthi, R.
Danquah, Michael
author_sort Agyei, D.
building Curtin Institutional Repository
collection Online Access
description This chapter focuses on the metabolism of genus Lactobacillus, with emphasis on the proteolytic potential of the well-known species in order to highlight their potential use in the production of bioactive peptides. Fermentation activities for most of the literature references used in this chapter were conducted in batch mode but the focus of the studies was not on comparing fermentation modes and their effects on proteinase yields. The vast diversity of lactobacilli proteinases represents an industrially feasible avenue for exploitation in biotechnological applications. Continued improvement of proteinase yields depends on a number of factors: identification of highly proteolytic strains, improvement of proteinase yields via optimisation of mediacomponent and process parameters and efficient product recovery. Successfully addressing these issues will require a multidisciplinary approach, encompassing fields such as microbiology, statistics and mathematical modelling and bioprocess engineering.
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publishDate 2013
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spelling curtin-20.500.11937-73132017-09-13T14:34:28Z Production of Lactobacilli Proteinases for the Manufacture of Bioactive Peptides: Part I-Upstream Processes Agyei, D. Potumarthi, R. Danquah, Michael This chapter focuses on the metabolism of genus Lactobacillus, with emphasis on the proteolytic potential of the well-known species in order to highlight their potential use in the production of bioactive peptides. Fermentation activities for most of the literature references used in this chapter were conducted in batch mode but the focus of the studies was not on comparing fermentation modes and their effects on proteinase yields. The vast diversity of lactobacilli proteinases represents an industrially feasible avenue for exploitation in biotechnological applications. Continued improvement of proteinase yields depends on a number of factors: identification of highly proteolytic strains, improvement of proteinase yields via optimisation of mediacomponent and process parameters and efficient product recovery. Successfully addressing these issues will require a multidisciplinary approach, encompassing fields such as microbiology, statistics and mathematical modelling and bioprocess engineering. 2013 Book Chapter http://hdl.handle.net/20.500.11937/7313 10.1002/9781118375082.ch10 restricted
spellingShingle Agyei, D.
Potumarthi, R.
Danquah, Michael
Production of Lactobacilli Proteinases for the Manufacture of Bioactive Peptides: Part I-Upstream Processes
title Production of Lactobacilli Proteinases for the Manufacture of Bioactive Peptides: Part I-Upstream Processes
title_full Production of Lactobacilli Proteinases for the Manufacture of Bioactive Peptides: Part I-Upstream Processes
title_fullStr Production of Lactobacilli Proteinases for the Manufacture of Bioactive Peptides: Part I-Upstream Processes
title_full_unstemmed Production of Lactobacilli Proteinases for the Manufacture of Bioactive Peptides: Part I-Upstream Processes
title_short Production of Lactobacilli Proteinases for the Manufacture of Bioactive Peptides: Part I-Upstream Processes
title_sort production of lactobacilli proteinases for the manufacture of bioactive peptides: part i-upstream processes
url http://hdl.handle.net/20.500.11937/7313