Symptoms and feelings valued by patients after a percutaneous coronary intervention: A discrete-choice experiment to inform development of a new patient-reported outcome

Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Objective To inform the development of a patient-reported outcome measure, the aim of this study was to identify which symptoms and feelings following percutaneous coronary intervention (PCI) are mos...

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Main Authors: Barker, A., Peeters, G., Morello, R., Norman, Richard, Ayton, D., Lefkovits, J., Brennan, Angela, Evans, S., Zalcberg, J., Reid, C., Ahern, S., Soh, S., Stoelwinder, J., McNeil, J.
Format: Journal Article
Published: BM J Group 2018
Online Access:http://purl.org/au-research/grants/nhmrc/1136372
http://hdl.handle.net/20.500.11937/73074
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author Barker, A.
Peeters, G.
Morello, R.
Norman, Richard
Ayton, D.
Lefkovits, J.
Brennan, Angela
Evans, S.
Zalcberg, J.
Reid, C.
Ahern, S.
Soh, S.
Stoelwinder, J.
McNeil, J.
author_facet Barker, A.
Peeters, G.
Morello, R.
Norman, Richard
Ayton, D.
Lefkovits, J.
Brennan, Angela
Evans, S.
Zalcberg, J.
Reid, C.
Ahern, S.
Soh, S.
Stoelwinder, J.
McNeil, J.
author_sort Barker, A.
building Curtin Institutional Repository
collection Online Access
description Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Objective To inform the development of a patient-reported outcome measure, the aim of this study was to identify which symptoms and feelings following percutaneous coronary intervention (PCI) are most important to patients. Design Discrete-choice experiment consisting of two hypothetical scenarios of 10 symptoms and feelings (pain or discomfort; shortness of breath; concern/worry about heart problems; tiredness; confidence to do usual activities; ability to do usual activities; happiness; sleep disturbance; dizziness or light-headedness and bruising) experienced after PCI, described by three levels (never, some of the time, most of the time). Preference weights were estimated using a conditional logit model. Setting Four Australian public hospitals that contribute to the Victorian Cardiac Outcomes Registry (VCOR) and a private insurer's claim database. Participants 138 people aged >18 years who had undergone a PCI in the previous 6 months. Main outcome measures Patient preferences via trade-offs between 10 feelings and symptoms. Results Of the 138 individuals recruited, 129 (93%) completed all 16 choice sets. Conditional logit parameter estimates were mostly monotonic (eg, moving to worse levels for each individual symptom and feeling made the option less attractive). When comparing the magnitude of the coefficients (based on the coefficient of the worst level relative to best level in each item), feeling unhappy was the symptom or feeling that most influenced perception of a least-preferred PCI outcome (OR 0.42, 95% CI 0.34 to 0.51, p<0.0001) and the least influential was bruising (OR 0.81, 95% CI 0.67 to 0.99, p=0.04). Conclusion This study provides new insights into how patients value symptoms and feelings they experience following a PCI.
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spelling curtin-20.500.11937-730742023-04-05T06:20:48Z Symptoms and feelings valued by patients after a percutaneous coronary intervention: A discrete-choice experiment to inform development of a new patient-reported outcome Barker, A. Peeters, G. Morello, R. Norman, Richard Ayton, D. Lefkovits, J. Brennan, Angela Evans, S. Zalcberg, J. Reid, C. Ahern, S. Soh, S. Stoelwinder, J. McNeil, J. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Objective To inform the development of a patient-reported outcome measure, the aim of this study was to identify which symptoms and feelings following percutaneous coronary intervention (PCI) are most important to patients. Design Discrete-choice experiment consisting of two hypothetical scenarios of 10 symptoms and feelings (pain or discomfort; shortness of breath; concern/worry about heart problems; tiredness; confidence to do usual activities; ability to do usual activities; happiness; sleep disturbance; dizziness or light-headedness and bruising) experienced after PCI, described by three levels (never, some of the time, most of the time). Preference weights were estimated using a conditional logit model. Setting Four Australian public hospitals that contribute to the Victorian Cardiac Outcomes Registry (VCOR) and a private insurer's claim database. Participants 138 people aged >18 years who had undergone a PCI in the previous 6 months. Main outcome measures Patient preferences via trade-offs between 10 feelings and symptoms. Results Of the 138 individuals recruited, 129 (93%) completed all 16 choice sets. Conditional logit parameter estimates were mostly monotonic (eg, moving to worse levels for each individual symptom and feeling made the option less attractive). When comparing the magnitude of the coefficients (based on the coefficient of the worst level relative to best level in each item), feeling unhappy was the symptom or feeling that most influenced perception of a least-preferred PCI outcome (OR 0.42, 95% CI 0.34 to 0.51, p<0.0001) and the least influential was bruising (OR 0.81, 95% CI 0.67 to 0.99, p=0.04). Conclusion This study provides new insights into how patients value symptoms and feelings they experience following a PCI. 2018 Journal Article http://hdl.handle.net/20.500.11937/73074 10.1136/bmjopen-2018-023141 http://purl.org/au-research/grants/nhmrc/1136372 http://purl.org/au-research/grants/nhmrc/1067236 http://creativecommons.org/licenses/by-nc/4.0/ BM J Group fulltext
spellingShingle Barker, A.
Peeters, G.
Morello, R.
Norman, Richard
Ayton, D.
Lefkovits, J.
Brennan, Angela
Evans, S.
Zalcberg, J.
Reid, C.
Ahern, S.
Soh, S.
Stoelwinder, J.
McNeil, J.
Symptoms and feelings valued by patients after a percutaneous coronary intervention: A discrete-choice experiment to inform development of a new patient-reported outcome
title Symptoms and feelings valued by patients after a percutaneous coronary intervention: A discrete-choice experiment to inform development of a new patient-reported outcome
title_full Symptoms and feelings valued by patients after a percutaneous coronary intervention: A discrete-choice experiment to inform development of a new patient-reported outcome
title_fullStr Symptoms and feelings valued by patients after a percutaneous coronary intervention: A discrete-choice experiment to inform development of a new patient-reported outcome
title_full_unstemmed Symptoms and feelings valued by patients after a percutaneous coronary intervention: A discrete-choice experiment to inform development of a new patient-reported outcome
title_short Symptoms and feelings valued by patients after a percutaneous coronary intervention: A discrete-choice experiment to inform development of a new patient-reported outcome
title_sort symptoms and feelings valued by patients after a percutaneous coronary intervention: a discrete-choice experiment to inform development of a new patient-reported outcome
url http://purl.org/au-research/grants/nhmrc/1136372
http://purl.org/au-research/grants/nhmrc/1136372
http://hdl.handle.net/20.500.11937/73074