In vitro investigation of bioactivities of solid-state fermented lupin, quinoa and wheat using Lactobacillus spp.
This study is an in-vitro investigation of the health-promoting properties of fermented whole-grain lupin, quinoa and wheat, using 72 h solid-state fermentation by Lactobacillus reuteri K777 and Lb. plantarum K779. Antiproliferative activity against Caco-2 and MCF-7 cancer cell lines (tumour cell li...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
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Elsevier BV
2019
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| Online Access: | http://hdl.handle.net/20.500.11937/72853 |
| _version_ | 1848762858523852800 |
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| author | Ayyash, M. Johnson, Stuart Liu, S. Mesmari, N. Dahmani, S. Al Dhaheri, A. Kizhakkayil, J. |
| author_facet | Ayyash, M. Johnson, Stuart Liu, S. Mesmari, N. Dahmani, S. Al Dhaheri, A. Kizhakkayil, J. |
| author_sort | Ayyash, M. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | This study is an in-vitro investigation of the health-promoting properties of fermented whole-grain lupin, quinoa and wheat, using 72 h solid-state fermentation by Lactobacillus reuteri K777 and Lb. plantarum K779. Antiproliferative activity against Caco-2 and MCF-7 cancer cell lines (tumour cell lines of intestinal and mammary origin, respectively) was investigated, as well as a-amylase and a-glucosidase inhibition, antihypertensive, antioxidant and proteolytic activities. ABTS antioxidant activities of fermented lupin (FL, 55% w/v), quinoa (FQ, 55% w/v) and wheat (FW, 55% w/v) ranged from ~12.0% to 55.0%, ~17.6% to 73.0%, and ~29.0% to 26.0%, respectively. Lupin, quinoa and wheat fermented by L. plantarum had pronounced antihypertensive activities (~85%). The a-glucosidase inhibition in FL was higher than that of FQ and FW. The magnitude of the antiproliferative activities of FL was markedly greater (p < 0.05) than of FQ and FW by approximately three-fold and two-folds against Caco-2 and MCF-7 cell lines, respectively. |
| first_indexed | 2025-11-14T10:54:15Z |
| format | Journal Article |
| id | curtin-20.500.11937-72853 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:54:15Z |
| publishDate | 2019 |
| publisher | Elsevier BV |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-728532019-02-12T03:04:01Z In vitro investigation of bioactivities of solid-state fermented lupin, quinoa and wheat using Lactobacillus spp. Ayyash, M. Johnson, Stuart Liu, S. Mesmari, N. Dahmani, S. Al Dhaheri, A. Kizhakkayil, J. This study is an in-vitro investigation of the health-promoting properties of fermented whole-grain lupin, quinoa and wheat, using 72 h solid-state fermentation by Lactobacillus reuteri K777 and Lb. plantarum K779. Antiproliferative activity against Caco-2 and MCF-7 cancer cell lines (tumour cell lines of intestinal and mammary origin, respectively) was investigated, as well as a-amylase and a-glucosidase inhibition, antihypertensive, antioxidant and proteolytic activities. ABTS antioxidant activities of fermented lupin (FL, 55% w/v), quinoa (FQ, 55% w/v) and wheat (FW, 55% w/v) ranged from ~12.0% to 55.0%, ~17.6% to 73.0%, and ~29.0% to 26.0%, respectively. Lupin, quinoa and wheat fermented by L. plantarum had pronounced antihypertensive activities (~85%). The a-glucosidase inhibition in FL was higher than that of FQ and FW. The magnitude of the antiproliferative activities of FL was markedly greater (p < 0.05) than of FQ and FW by approximately three-fold and two-folds against Caco-2 and MCF-7 cell lines, respectively. 2019 Journal Article http://hdl.handle.net/20.500.11937/72853 10.1016/j.foodchem.2018.09.031 Elsevier BV restricted |
| spellingShingle | Ayyash, M. Johnson, Stuart Liu, S. Mesmari, N. Dahmani, S. Al Dhaheri, A. Kizhakkayil, J. In vitro investigation of bioactivities of solid-state fermented lupin, quinoa and wheat using Lactobacillus spp. |
| title | In vitro investigation of bioactivities of solid-state fermented lupin, quinoa and wheat using Lactobacillus spp. |
| title_full | In vitro investigation of bioactivities of solid-state fermented lupin, quinoa and wheat using Lactobacillus spp. |
| title_fullStr | In vitro investigation of bioactivities of solid-state fermented lupin, quinoa and wheat using Lactobacillus spp. |
| title_full_unstemmed | In vitro investigation of bioactivities of solid-state fermented lupin, quinoa and wheat using Lactobacillus spp. |
| title_short | In vitro investigation of bioactivities of solid-state fermented lupin, quinoa and wheat using Lactobacillus spp. |
| title_sort | in vitro investigation of bioactivities of solid-state fermented lupin, quinoa and wheat using lactobacillus spp. |
| url | http://hdl.handle.net/20.500.11937/72853 |