The aging diver: Endothelial biochemistry and its potential implications for cardiovascular health

© 2015, South Pacific Underwater Medicine Society. All rights reserved. Divers are exposed to circulatory stress that directly affects the endothelial lining of blood vessels, and even asymptomatic dives are associated with inflammatory responses, microparticle release and endothelial dysfunction. A...

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Main Authors: Ardestani, S., Buzzacott, Peter, Eftedal, I.
Format: Journal Article
Published: 2015
Online Access:http://hdl.handle.net/20.500.11937/72845
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author Ardestani, S.
Buzzacott, Peter
Eftedal, I.
author_facet Ardestani, S.
Buzzacott, Peter
Eftedal, I.
author_sort Ardestani, S.
building Curtin Institutional Repository
collection Online Access
description © 2015, South Pacific Underwater Medicine Society. All rights reserved. Divers are exposed to circulatory stress that directly affects the endothelial lining of blood vessels, and even asymptomatic dives are associated with inflammatory responses, microparticle release and endothelial dysfunction. As humans age, there is a relative increase in the risk of cardiovascular disease, attributed in part to declining endothelial function. Whether extensive diving in the older diver increases the risk of disease as a result of accumulated circulatory stress, or provides protection through processes of acclimatization remains an open question. We provide a brief review of current knowledge about the separate effects of diving and aging on the vascular endothelium in humans and rodents, and discuss the available data on their combined effects. The aim is to elucidate possible outcomes of the interplay between exogenous and endogenous stress factors for endothelial function and to question potential implications for cardiovascular health in the aging diver.
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spelling curtin-20.500.11937-728452018-12-13T09:14:34Z The aging diver: Endothelial biochemistry and its potential implications for cardiovascular health Ardestani, S. Buzzacott, Peter Eftedal, I. © 2015, South Pacific Underwater Medicine Society. All rights reserved. Divers are exposed to circulatory stress that directly affects the endothelial lining of blood vessels, and even asymptomatic dives are associated with inflammatory responses, microparticle release and endothelial dysfunction. As humans age, there is a relative increase in the risk of cardiovascular disease, attributed in part to declining endothelial function. Whether extensive diving in the older diver increases the risk of disease as a result of accumulated circulatory stress, or provides protection through processes of acclimatization remains an open question. We provide a brief review of current knowledge about the separate effects of diving and aging on the vascular endothelium in humans and rodents, and discuss the available data on their combined effects. The aim is to elucidate possible outcomes of the interplay between exogenous and endogenous stress factors for endothelial function and to question potential implications for cardiovascular health in the aging diver. 2015 Journal Article http://hdl.handle.net/20.500.11937/72845 restricted
spellingShingle Ardestani, S.
Buzzacott, Peter
Eftedal, I.
The aging diver: Endothelial biochemistry and its potential implications for cardiovascular health
title The aging diver: Endothelial biochemistry and its potential implications for cardiovascular health
title_full The aging diver: Endothelial biochemistry and its potential implications for cardiovascular health
title_fullStr The aging diver: Endothelial biochemistry and its potential implications for cardiovascular health
title_full_unstemmed The aging diver: Endothelial biochemistry and its potential implications for cardiovascular health
title_short The aging diver: Endothelial biochemistry and its potential implications for cardiovascular health
title_sort aging diver: endothelial biochemistry and its potential implications for cardiovascular health
url http://hdl.handle.net/20.500.11937/72845