GAW20: Methods and strategies for the new frontiers of epigenetics and pharmacogenomics
© 2018 The Author(s). GAW20 provided a platform for developing and evaluating statistical methods to analyze human lipid-related phenotypes, DNA methylation, and single-nucleotide markers in a study involving a pharmaceutical intervention. In this article, we present an overview of the data sets and...
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| Format: | Journal Article |
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2018
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| Online Access: | http://hdl.handle.net/20.500.11937/72679 |
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| author | Tintle, N. Fardo, D. De Andrade, M. Aslibekyan, S. Bailey, J. Bermejo, J. Cantor, R. Ghosh, S. Melton, Phillip Wang, X. MacCluer, J. Almasy, L. |
| author_facet | Tintle, N. Fardo, D. De Andrade, M. Aslibekyan, S. Bailey, J. Bermejo, J. Cantor, R. Ghosh, S. Melton, Phillip Wang, X. MacCluer, J. Almasy, L. |
| author_sort | Tintle, N. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © 2018 The Author(s). GAW20 provided a platform for developing and evaluating statistical methods to analyze human lipid-related phenotypes, DNA methylation, and single-nucleotide markers in a study involving a pharmaceutical intervention. In this article, we present an overview of the data sets and the contributions analyzing these data. The data, donated by the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) investigators, included data from 188 families (N = 1105) which included genome-wide DNA methylation data before and after a 3-week treatment with fenofibrate, single-nucleotide polymorphisms, metabolic syndrome components before and after treatment, and a variety of covariates. The contributions from individual research groups were extensively discussed prior, during, and after the Workshop in groups based on discussion themes, before being submitted for publication. |
| first_indexed | 2025-11-14T10:53:33Z |
| format | Journal Article |
| id | curtin-20.500.11937-72679 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:53:33Z |
| publishDate | 2018 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-726792019-03-18T06:23:13Z GAW20: Methods and strategies for the new frontiers of epigenetics and pharmacogenomics Tintle, N. Fardo, D. De Andrade, M. Aslibekyan, S. Bailey, J. Bermejo, J. Cantor, R. Ghosh, S. Melton, Phillip Wang, X. MacCluer, J. Almasy, L. © 2018 The Author(s). GAW20 provided a platform for developing and evaluating statistical methods to analyze human lipid-related phenotypes, DNA methylation, and single-nucleotide markers in a study involving a pharmaceutical intervention. In this article, we present an overview of the data sets and the contributions analyzing these data. The data, donated by the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) investigators, included data from 188 families (N = 1105) which included genome-wide DNA methylation data before and after a 3-week treatment with fenofibrate, single-nucleotide polymorphisms, metabolic syndrome components before and after treatment, and a variety of covariates. The contributions from individual research groups were extensively discussed prior, during, and after the Workshop in groups based on discussion themes, before being submitted for publication. 2018 Journal Article http://hdl.handle.net/20.500.11937/72679 10.1186/s12919-018-0113-1 http://creativecommons.org/licenses/by/4.0/ fulltext |
| spellingShingle | Tintle, N. Fardo, D. De Andrade, M. Aslibekyan, S. Bailey, J. Bermejo, J. Cantor, R. Ghosh, S. Melton, Phillip Wang, X. MacCluer, J. Almasy, L. GAW20: Methods and strategies for the new frontiers of epigenetics and pharmacogenomics |
| title | GAW20: Methods and strategies for the new frontiers of epigenetics and pharmacogenomics |
| title_full | GAW20: Methods and strategies for the new frontiers of epigenetics and pharmacogenomics |
| title_fullStr | GAW20: Methods and strategies for the new frontiers of epigenetics and pharmacogenomics |
| title_full_unstemmed | GAW20: Methods and strategies for the new frontiers of epigenetics and pharmacogenomics |
| title_short | GAW20: Methods and strategies for the new frontiers of epigenetics and pharmacogenomics |
| title_sort | gaw20: methods and strategies for the new frontiers of epigenetics and pharmacogenomics |
| url | http://hdl.handle.net/20.500.11937/72679 |