Utility of an Alzheimer's Disease Risk-Weighted Polygenic Risk Score for Predicting Rates of Cognitive Decline in Preclinical Alzheimer's Disease: A Prospective Longitudinal Study.

Utility of an Alzheimer's Disease Risk-Weighted Polygenic Risk Score for Predicting Rates of Cognitive Decline in Preclinical Alzheimer's Disease: A Prospective Longitudinal Study.

BACKGROUND: With the exception of APOE, genetic variants associated with increased Alzheimer's disease (AD) risk are characterized by small effect sizes. Polygenic risk scores (PRS) have shown utility in predicting AD risk; however, their utility for predicting decline in cognition at preclinic...

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Bibliographic Details
Main Authors: Porter, T., Burnham, S., Milicic, L., Savage, G., Maruff, P., Lim, Y., Li, Q., Ames, D., Masters, C., Rainey-Smith, S., Rowe, C., Salvado, O., Groth, D., Verdile, Giuseppe, Villemagne, V., Laws, S., AIBL Research Group
Format: Journal Article
Published: IOS Press 2018
Online Access:http://hdl.handle.net/20.500.11937/72666

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