Age, weight and decompression sickness in rats

© 2015 Taylor and Francis. Objective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving...

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Main Authors: Buzzacott, Peter, Theron, M., Mazur, A., Wang, Q., Lambrechts, K., Eftedal, I., Ardestani, S., Guerrero, F.
Format: Journal Article
Published: 2016
Online Access:http://hdl.handle.net/20.500.11937/72585
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author Buzzacott, Peter
Theron, M.
Mazur, A.
Wang, Q.
Lambrechts, K.
Eftedal, I.
Ardestani, S.
Guerrero, F.
author_facet Buzzacott, Peter
Theron, M.
Mazur, A.
Wang, Q.
Lambrechts, K.
Eftedal, I.
Ardestani, S.
Guerrero, F.
author_sort Buzzacott, Peter
building Curtin Institutional Repository
collection Online Access
description © 2015 Taylor and Francis. Objective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving rats were re-dived using the same compression-decompression profile. Results: In this experiment, there was a clear difference between DCS outcome at ages 11 or 13 weeks in matched rats (p = 0.002). Discussion: Even with weight included in the model, age was significantly associated with DCS (p = 0.01), yet after removal of weight the association was much stronger (p = 0.002). Conclusion: We believe that age is likely to be found associated with the probability of DCS in a larger dataset with a wider range of parameters, after accounting for the effect of weight.
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spelling curtin-20.500.11937-725852018-12-13T09:34:31Z Age, weight and decompression sickness in rats Buzzacott, Peter Theron, M. Mazur, A. Wang, Q. Lambrechts, K. Eftedal, I. Ardestani, S. Guerrero, F. © 2015 Taylor and Francis. Objective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving rats were re-dived using the same compression-decompression profile. Results: In this experiment, there was a clear difference between DCS outcome at ages 11 or 13 weeks in matched rats (p = 0.002). Discussion: Even with weight included in the model, age was significantly associated with DCS (p = 0.01), yet after removal of weight the association was much stronger (p = 0.002). Conclusion: We believe that age is likely to be found associated with the probability of DCS in a larger dataset with a wider range of parameters, after accounting for the effect of weight. 2016 Journal Article http://hdl.handle.net/20.500.11937/72585 10.3109/13813455.2016.1140787 restricted
spellingShingle Buzzacott, Peter
Theron, M.
Mazur, A.
Wang, Q.
Lambrechts, K.
Eftedal, I.
Ardestani, S.
Guerrero, F.
Age, weight and decompression sickness in rats
title Age, weight and decompression sickness in rats
title_full Age, weight and decompression sickness in rats
title_fullStr Age, weight and decompression sickness in rats
title_full_unstemmed Age, weight and decompression sickness in rats
title_short Age, weight and decompression sickness in rats
title_sort age, weight and decompression sickness in rats
url http://hdl.handle.net/20.500.11937/72585