Two subtypes of symptomatic joint hypermobility: A descriptive study using latent class analysis
Objective: To investigate a cohort of children with symptomatic joint hypermobility. Methods: Case notes for 318 children with joint hypermobility attending a rheumatology clinic were reviewed for clinical presentation, medical history, psychosocial factors and physical examination findings. Seven k...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
| Published: |
BMJ Group
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/72276 |
| _version_ | 1848762707015106560 |
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| author | Di Mattia, F. Fary, Robyn Murray, K. Howie, E. Smith, Anne Morris, Susan |
| author_facet | Di Mattia, F. Fary, Robyn Murray, K. Howie, E. Smith, Anne Morris, Susan |
| author_sort | Di Mattia, F. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Objective: To investigate a cohort of children with symptomatic joint hypermobility. Methods: Case notes for 318 children with joint hypermobility attending a rheumatology clinic were reviewed for clinical presentation, medical history, psychosocial factors and physical examination findings. Seven key variables were extracted and used as indicator variables in a latent class analysis to estimate the presence and number of subgroups of children with symptomatic joint hypermobility. Results: Two subgroups with differing clinical presentations were identified accounting for age and gender: an 'athletic-persistent' class (62%) characterised by higher probabilities for recurrent and chronic musculoskeletal pain, and less severe hypermobility; and a 'systemic-profound' class (38%) characterised by generalised hypermobility, recurrent musculoskeletal pain, gastro-oesophageal reflux and motor delay. Conclusion: Findings suggest the presence of two distinct presentations of children with hypermobility. This finding may be important for clinical decision-making and management of this group of children. |
| first_indexed | 2025-11-14T10:51:50Z |
| format | Journal Article |
| id | curtin-20.500.11937-72276 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:51:50Z |
| publishDate | 2018 |
| publisher | BMJ Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-722762019-01-15T06:49:56Z Two subtypes of symptomatic joint hypermobility: A descriptive study using latent class analysis Di Mattia, F. Fary, Robyn Murray, K. Howie, E. Smith, Anne Morris, Susan Objective: To investigate a cohort of children with symptomatic joint hypermobility. Methods: Case notes for 318 children with joint hypermobility attending a rheumatology clinic were reviewed for clinical presentation, medical history, psychosocial factors and physical examination findings. Seven key variables were extracted and used as indicator variables in a latent class analysis to estimate the presence and number of subgroups of children with symptomatic joint hypermobility. Results: Two subgroups with differing clinical presentations were identified accounting for age and gender: an 'athletic-persistent' class (62%) characterised by higher probabilities for recurrent and chronic musculoskeletal pain, and less severe hypermobility; and a 'systemic-profound' class (38%) characterised by generalised hypermobility, recurrent musculoskeletal pain, gastro-oesophageal reflux and motor delay. Conclusion: Findings suggest the presence of two distinct presentations of children with hypermobility. This finding may be important for clinical decision-making and management of this group of children. 2018 Journal Article http://hdl.handle.net/20.500.11937/72276 10.1136/archdischild-2017-314149 BMJ Group restricted |
| spellingShingle | Di Mattia, F. Fary, Robyn Murray, K. Howie, E. Smith, Anne Morris, Susan Two subtypes of symptomatic joint hypermobility: A descriptive study using latent class analysis |
| title | Two subtypes of symptomatic joint hypermobility: A descriptive study using latent class analysis |
| title_full | Two subtypes of symptomatic joint hypermobility: A descriptive study using latent class analysis |
| title_fullStr | Two subtypes of symptomatic joint hypermobility: A descriptive study using latent class analysis |
| title_full_unstemmed | Two subtypes of symptomatic joint hypermobility: A descriptive study using latent class analysis |
| title_short | Two subtypes of symptomatic joint hypermobility: A descriptive study using latent class analysis |
| title_sort | two subtypes of symptomatic joint hypermobility: a descriptive study using latent class analysis |
| url | http://hdl.handle.net/20.500.11937/72276 |