Organochlorine Levels in Plasma and Risk of Multiple Myeloma
CONCLUSION: Our study provides evidence that organochlorines contribute to the risk of MM.RESULTS: Most organochlorine analytes showed a significant association with MM. The strongest association (highest vs lowest quartile) was oxychlordane (odds ratio?=?7.44; 95% confidence interval?=?4.19 to 13.2...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/72196 |
| _version_ | 1848762685776199680 |
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| author | Weber, L. Song, K. Boyle, Terry Gaudreau, �. Lai, A. Sutherland, H. LeBlanc, A. Spinelli, J. |
| author_facet | Weber, L. Song, K. Boyle, Terry Gaudreau, �. Lai, A. Sutherland, H. LeBlanc, A. Spinelli, J. |
| author_sort | Weber, L. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | CONCLUSION: Our study provides evidence that organochlorines contribute to the risk of MM.RESULTS: Most organochlorine analytes showed a significant association with MM. The strongest association (highest vs lowest quartile) was oxychlordane (odds ratio?=?7.44; 95% confidence interval?=?4.19 to 13.21). No heterogeneity was detected between organochlorines levels and MM subtypes. Only oxychlordane and ß-hexachlorocyclohexane (ß-HCCH) were identified as significant independent predictors of MM.OBJECTIVE: The aim of this study was to estimate the association between organochlorine pesticides and polychlorinated biphenyls (PCBs) and multiple myeloma (MM).METHODS: The risk of MM from organochlorine compounds was examined in a population-based case-control study in British Columbia, Canada. Congeners of PCBs and pesticides or pesticide metabolites were measured in plasma of 325 cases and 327 controls. |
| first_indexed | 2025-11-14T10:51:30Z |
| format | Journal Article |
| id | curtin-20.500.11937-72196 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:51:30Z |
| publishDate | 2018 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-721962018-12-13T09:31:55Z Organochlorine Levels in Plasma and Risk of Multiple Myeloma Weber, L. Song, K. Boyle, Terry Gaudreau, �. Lai, A. Sutherland, H. LeBlanc, A. Spinelli, J. CONCLUSION: Our study provides evidence that organochlorines contribute to the risk of MM.RESULTS: Most organochlorine analytes showed a significant association with MM. The strongest association (highest vs lowest quartile) was oxychlordane (odds ratio?=?7.44; 95% confidence interval?=?4.19 to 13.21). No heterogeneity was detected between organochlorines levels and MM subtypes. Only oxychlordane and ß-hexachlorocyclohexane (ß-HCCH) were identified as significant independent predictors of MM.OBJECTIVE: The aim of this study was to estimate the association between organochlorine pesticides and polychlorinated biphenyls (PCBs) and multiple myeloma (MM).METHODS: The risk of MM from organochlorine compounds was examined in a population-based case-control study in British Columbia, Canada. Congeners of PCBs and pesticides or pesticide metabolites were measured in plasma of 325 cases and 327 controls. 2018 Journal Article http://hdl.handle.net/20.500.11937/72196 10.1097/JOM.0000000000001387 restricted |
| spellingShingle | Weber, L. Song, K. Boyle, Terry Gaudreau, �. Lai, A. Sutherland, H. LeBlanc, A. Spinelli, J. Organochlorine Levels in Plasma and Risk of Multiple Myeloma |
| title | Organochlorine Levels in Plasma and Risk of Multiple Myeloma |
| title_full | Organochlorine Levels in Plasma and Risk of Multiple Myeloma |
| title_fullStr | Organochlorine Levels in Plasma and Risk of Multiple Myeloma |
| title_full_unstemmed | Organochlorine Levels in Plasma and Risk of Multiple Myeloma |
| title_short | Organochlorine Levels in Plasma and Risk of Multiple Myeloma |
| title_sort | organochlorine levels in plasma and risk of multiple myeloma |
| url | http://hdl.handle.net/20.500.11937/72196 |