Peripheral quantitative computed tomography (pQCT) reveals low bone mineral density in adolescents with motor difficulties

© 2015, International Osteoporosis Foundation and National Osteoporosis Foundation. Summary: This is the first reported study to describe local bone mineral density, assess parameters of fracture risk and report history of fractures in adolescents with motor difficulties. Motor difficulties evidence...

Full description

Bibliographic Details
Main Authors: Hands, B., Chivers, P., McIntyre, F., Bervenotti, F., Blee, Tanya, Beeson, B., Bettenay, F., Siafarikas, A.
Format: Journal Article
Published: Springer 2015
Online Access:http://hdl.handle.net/20.500.11937/71966
_version_ 1848762622390829056
author Hands, B.
Chivers, P.
McIntyre, F.
Bervenotti, F.
Blee, Tanya
Beeson, B.
Bettenay, F.
Siafarikas, A.
author_facet Hands, B.
Chivers, P.
McIntyre, F.
Bervenotti, F.
Blee, Tanya
Beeson, B.
Bettenay, F.
Siafarikas, A.
author_sort Hands, B.
building Curtin Institutional Repository
collection Online Access
description © 2015, International Osteoporosis Foundation and National Osteoporosis Foundation. Summary: This is the first reported study to describe local bone mineral density, assess parameters of fracture risk and report history of fractures in adolescents with motor difficulties. Motor difficulties evidenced by poor coordination in adolescence should be considered a new risk factor for below-average bone strength and structure and fracture risk. Introduction: Adolescents with motor difficulties are characterised by poor coordination and low levels of physical activity and fitness. It is possible these deficits translate into below-average bone strength and structure. The objectives of this study were to describe local bone mineral density (BMD), assess parameters of fracture risk (stress–strain index, SSI) and report history of fractures in this group. Methods: Thirty-three adolescents (13 females), mean age of 14.3 (SD = 1.5) years, with motor difficulties underwent peripheral quantitative computed tomography (pQCT) measurements at proximal (66 %) and distal (4 %) sites of the non-dominant radius (R4 and R66) and tibia (T4 and T66). One sample t test was used to compare Z-scores for total BMD, trabecular density, cortical density and stress strain index (SSI) against standardized norms. Results: Significant differences were present at R4 total density mean Z-score = -0.85 (SD = 0.7, p < 0.001), R66 cortical density mean Z-score = -0.74 (SD = 1.97, p = 0.038), R66 SSI mean Z-score = -1.00 (SD = 1.08, p < 0.001) and T66 SSI mean Z-score = -0.70 (SD = 1.15, p < 0.001). There was a higher incidence of fractures (26.9 %) compared to the normal population (3–9 %). Conclusions: Motor difficulties in adolescence should be considered a risk factor for below-average bone strength and structure and fracture risk. Strategies are needed to improve bone health in this high-risk-group.
first_indexed 2025-11-14T10:50:30Z
format Journal Article
id curtin-20.500.11937-71966
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T10:50:30Z
publishDate 2015
publisher Springer
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-719662018-12-13T09:35:02Z Peripheral quantitative computed tomography (pQCT) reveals low bone mineral density in adolescents with motor difficulties Hands, B. Chivers, P. McIntyre, F. Bervenotti, F. Blee, Tanya Beeson, B. Bettenay, F. Siafarikas, A. © 2015, International Osteoporosis Foundation and National Osteoporosis Foundation. Summary: This is the first reported study to describe local bone mineral density, assess parameters of fracture risk and report history of fractures in adolescents with motor difficulties. Motor difficulties evidenced by poor coordination in adolescence should be considered a new risk factor for below-average bone strength and structure and fracture risk. Introduction: Adolescents with motor difficulties are characterised by poor coordination and low levels of physical activity and fitness. It is possible these deficits translate into below-average bone strength and structure. The objectives of this study were to describe local bone mineral density (BMD), assess parameters of fracture risk (stress–strain index, SSI) and report history of fractures in this group. Methods: Thirty-three adolescents (13 females), mean age of 14.3 (SD = 1.5) years, with motor difficulties underwent peripheral quantitative computed tomography (pQCT) measurements at proximal (66 %) and distal (4 %) sites of the non-dominant radius (R4 and R66) and tibia (T4 and T66). One sample t test was used to compare Z-scores for total BMD, trabecular density, cortical density and stress strain index (SSI) against standardized norms. Results: Significant differences were present at R4 total density mean Z-score = -0.85 (SD = 0.7, p < 0.001), R66 cortical density mean Z-score = -0.74 (SD = 1.97, p = 0.038), R66 SSI mean Z-score = -1.00 (SD = 1.08, p < 0.001) and T66 SSI mean Z-score = -0.70 (SD = 1.15, p < 0.001). There was a higher incidence of fractures (26.9 %) compared to the normal population (3–9 %). Conclusions: Motor difficulties in adolescence should be considered a risk factor for below-average bone strength and structure and fracture risk. Strategies are needed to improve bone health in this high-risk-group. 2015 Journal Article http://hdl.handle.net/20.500.11937/71966 10.1007/s00198-015-3071-8 Springer restricted
spellingShingle Hands, B.
Chivers, P.
McIntyre, F.
Bervenotti, F.
Blee, Tanya
Beeson, B.
Bettenay, F.
Siafarikas, A.
Peripheral quantitative computed tomography (pQCT) reveals low bone mineral density in adolescents with motor difficulties
title Peripheral quantitative computed tomography (pQCT) reveals low bone mineral density in adolescents with motor difficulties
title_full Peripheral quantitative computed tomography (pQCT) reveals low bone mineral density in adolescents with motor difficulties
title_fullStr Peripheral quantitative computed tomography (pQCT) reveals low bone mineral density in adolescents with motor difficulties
title_full_unstemmed Peripheral quantitative computed tomography (pQCT) reveals low bone mineral density in adolescents with motor difficulties
title_short Peripheral quantitative computed tomography (pQCT) reveals low bone mineral density in adolescents with motor difficulties
title_sort peripheral quantitative computed tomography (pqct) reveals low bone mineral density in adolescents with motor difficulties
url http://hdl.handle.net/20.500.11937/71966