Lupin seed hydrolysate promotes G-protein-coupled receptor, intracellular Ca2+ and enhanced glycolytic metabolism-mediated insulin secretion from BRIN-BD11 pancreatic beta cells

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Lupin seed hydrolysate promotes G-protein-coupled receptor, intracellular Ca2+ and enhanced glycolytic metabolism-mediated insulin secretion from BRIN-BD11 pancreatic beta cells

Lupin seed proteins have been reported to exhibit hypoglycaemic effects in animals and humans following oral administration, however little is known about its mechanism of action. This study investigated the signalling pathway(s) responsible for the insulinotropic effect of the hydrolysate obtained...

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Bibliographic Details
Main Authors:	Tapadia, M., Carlessi, Rodrigo, Johnson, Stuart, Utikar, Ranjeet, Newsholme, Philip
Format:	Journal Article
Published:	Elsevier Ireland Ltd 2018
Online Access:	http://hdl.handle.net/20.500.11937/71848

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