PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

© The Author(s) 2018. Background. Hyperactivation of phosphoinositide 3-kinase (PI3K) signaling is common in cancers, but the precise role of the pathway in glioma biology remains to be determined. Some understanding of PI3K signaling mechanisms in brain cancer comes from studies on neural stem/prog...

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Bibliographic Details
Main Authors: Daniel, P., Filiz, G., Brown, D., Christie, M., Waring, P., Zhang, Y., Haynes, J., Pouton, C., Flanagan, D., Vincan, Elizabeth, Johns, T., Montgomery, K., Phillips, W., Mantamadiotis, T.
Format: Journal Article
Published: OXFORD UNIV PRESS INC 2018
Online Access:http://hdl.handle.net/20.500.11937/71836

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