An investigation of a vitamin D, ionised calcium and parathyroid hormone regulatory axis of cerebral capillary function: Implications for cognitive performance in ageing
Increasing evidence suggests compromised integrity of cerebral capillary endothelium precedes cognitive impairment and the onset of Alzheimer’s disease and vascular dementia. Results from in vivo animal model studies demonstrated novel findings of potential detrimental effects of hypervitaminosis D...
| Main Author: | |
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| Format: | Thesis |
| Language: | English |
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Curtin University
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/718 |
| _version_ | 1848743460168794112 |
|---|---|
| author | Lam, Virginie |
| author_facet | Lam, Virginie |
| author_sort | Lam, Virginie |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Increasing evidence suggests compromised integrity of cerebral capillary endothelium precedes cognitive impairment and the onset of Alzheimer’s disease and vascular dementia. Results from in vivo animal model studies demonstrated novel findings of potential detrimental effects of hypervitaminosis D on cerebral capillary integrity. Verbal episodic memory performance was negatively associated with vitamin D homeostasis in healthy older-aged adults. Overall, the use of vitamin D (VD) supplements should be considered only in context of VD deficiency. |
| first_indexed | 2025-11-14T05:45:55Z |
| format | Thesis |
| id | curtin-20.500.11937-718 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T05:45:55Z |
| publishDate | 2015 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-7182017-02-20T06:41:53Z An investigation of a vitamin D, ionised calcium and parathyroid hormone regulatory axis of cerebral capillary function: Implications for cognitive performance in ageing Lam, Virginie Increasing evidence suggests compromised integrity of cerebral capillary endothelium precedes cognitive impairment and the onset of Alzheimer’s disease and vascular dementia. Results from in vivo animal model studies demonstrated novel findings of potential detrimental effects of hypervitaminosis D on cerebral capillary integrity. Verbal episodic memory performance was negatively associated with vitamin D homeostasis in healthy older-aged adults. Overall, the use of vitamin D (VD) supplements should be considered only in context of VD deficiency. 2015 Thesis http://hdl.handle.net/20.500.11937/718 en Curtin University fulltext |
| spellingShingle | Lam, Virginie An investigation of a vitamin D, ionised calcium and parathyroid hormone regulatory axis of cerebral capillary function: Implications for cognitive performance in ageing |
| title | An investigation of a vitamin D, ionised calcium and parathyroid hormone regulatory axis of cerebral capillary function: Implications for cognitive performance in ageing |
| title_full | An investigation of a vitamin D, ionised calcium and parathyroid hormone regulatory axis of cerebral capillary function: Implications for cognitive performance in ageing |
| title_fullStr | An investigation of a vitamin D, ionised calcium and parathyroid hormone regulatory axis of cerebral capillary function: Implications for cognitive performance in ageing |
| title_full_unstemmed | An investigation of a vitamin D, ionised calcium and parathyroid hormone regulatory axis of cerebral capillary function: Implications for cognitive performance in ageing |
| title_short | An investigation of a vitamin D, ionised calcium and parathyroid hormone regulatory axis of cerebral capillary function: Implications for cognitive performance in ageing |
| title_sort | investigation of a vitamin d, ionised calcium and parathyroid hormone regulatory axis of cerebral capillary function: implications for cognitive performance in ageing |
| url | http://hdl.handle.net/20.500.11937/718 |