An introduction to glutamine metabolism

© 2017 by Taylor & Francis Group, LLC. Hlaziwetz and Habermann rst described glutamine as a molecule with biologically important properties in 1873. They suggested that the presence of ammonia (as NH4+), detected following hydrolysis of proteins, arose by degradation linked to amide groups fro...

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Main Authors: Cruzat, Vinicius, Newsholme, P.
Format: Book Chapter
Published: 2017
Online Access:http://hdl.handle.net/20.500.11937/71665
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author Cruzat, Vinicius
Newsholme, P.
author_facet Cruzat, Vinicius
Newsholme, P.
author_sort Cruzat, Vinicius
building Curtin Institutional Repository
collection Online Access
description © 2017 by Taylor & Francis Group, LLC. Hlaziwetz and Habermann rst described glutamine as a molecule with biologically important properties in 1873. They suggested that the presence of ammonia (as NH4+), detected following hydrolysis of proteins, arose by degradation linked to amide groups from glutamine and asparagine (Mora 2012). About 10 years later, Schulze and Bosshard isolated glutamine from a natural source (beet juice), and Damodaran and his collaborators contributed to the rst description of glutamine metabolism. However, the number of studies investigating glutamine metabolism and links to intermediary metabolism increased following the early work of Sir Hans Adolf Krebs (1900-1981), who was responsible for some of the most important discoveries in metabolic biochemistry and physiology in the twentieth century (Nobel Prize in Physiology or Medicine in 1953).
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spelling curtin-20.500.11937-716652018-12-13T09:31:54Z An introduction to glutamine metabolism Cruzat, Vinicius Newsholme, P. © 2017 by Taylor & Francis Group, LLC. Hlaziwetz and Habermann rst described glutamine as a molecule with biologically important properties in 1873. They suggested that the presence of ammonia (as NH4+), detected following hydrolysis of proteins, arose by degradation linked to amide groups from glutamine and asparagine (Mora 2012). About 10 years later, Schulze and Bosshard isolated glutamine from a natural source (beet juice), and Damodaran and his collaborators contributed to the rst description of glutamine metabolism. However, the number of studies investigating glutamine metabolism and links to intermediary metabolism increased following the early work of Sir Hans Adolf Krebs (1900-1981), who was responsible for some of the most important discoveries in metabolic biochemistry and physiology in the twentieth century (Nobel Prize in Physiology or Medicine in 1953). 2017 Book Chapter http://hdl.handle.net/20.500.11937/71665 10.1201/9781315373164 restricted
spellingShingle Cruzat, Vinicius
Newsholme, P.
An introduction to glutamine metabolism
title An introduction to glutamine metabolism
title_full An introduction to glutamine metabolism
title_fullStr An introduction to glutamine metabolism
title_full_unstemmed An introduction to glutamine metabolism
title_short An introduction to glutamine metabolism
title_sort introduction to glutamine metabolism
url http://hdl.handle.net/20.500.11937/71665