Pt nanoparticles supported on nitrogen-doped porous graphene for sensitive detection of Tadalafil

Graphene (GR) is one of the most promising candidates for utilization in the electroanalytical field because of its superior electrocatalytic activity, excellent electronic conductivity, and high chemical stability. However, the GR sheets usually tend to stack together with p-p interaction. The spon...

Full description

Bibliographic Details
Main Authors: Salah, A., Hassan, M., Liu, Jian, Li, M., Bo, X., Ndamanisha, J., Guo, L.
Format: Journal Article
Published: Academic Press 2018
Online Access:http://hdl.handle.net/20.500.11937/71549
_version_ 1848762509537837056
author Salah, A.
Hassan, M.
Liu, Jian
Li, M.
Bo, X.
Ndamanisha, J.
Guo, L.
author_facet Salah, A.
Hassan, M.
Liu, Jian
Li, M.
Bo, X.
Ndamanisha, J.
Guo, L.
author_sort Salah, A.
building Curtin Institutional Repository
collection Online Access
description Graphene (GR) is one of the most promising candidates for utilization in the electroanalytical field because of its superior electrocatalytic activity, excellent electronic conductivity, and high chemical stability. However, the GR sheets usually tend to stack together with p-p interaction. The spontaneous stacking leads to the aggregation of the GR sheets and imposes a negative feedback in the surface area of the GR, which obviously limits its electrochemical application. In this study, nitrogen-doped porous GR (NPGR) with different pore sizes is prepared by using silica (SiO2) as a template. The NPGR exhibits high surface area and porous structure, fulfilling the requirement for supporting materials. Being a support, the structural uniqueness and N dopants of NPGR facilitate the deposition of Pt nanoparticles (Pt NPs). The Pt NPs/NPGR composites integrate the structural properties of NPGR and catalytic properties of Pt NPs. A selective and sensitive electrochemical sensor was successfully developed for sensitive determination of Tadalafil (TAD), showing a concentration range of 1.30–488.9 µM and limit of detection of 0.268 µM.
first_indexed 2025-11-14T10:48:42Z
format Journal Article
id curtin-20.500.11937-71549
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T10:48:42Z
publishDate 2018
publisher Academic Press
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-715492019-01-29T00:55:35Z Pt nanoparticles supported on nitrogen-doped porous graphene for sensitive detection of Tadalafil Salah, A. Hassan, M. Liu, Jian Li, M. Bo, X. Ndamanisha, J. Guo, L. Graphene (GR) is one of the most promising candidates for utilization in the electroanalytical field because of its superior electrocatalytic activity, excellent electronic conductivity, and high chemical stability. However, the GR sheets usually tend to stack together with p-p interaction. The spontaneous stacking leads to the aggregation of the GR sheets and imposes a negative feedback in the surface area of the GR, which obviously limits its electrochemical application. In this study, nitrogen-doped porous GR (NPGR) with different pore sizes is prepared by using silica (SiO2) as a template. The NPGR exhibits high surface area and porous structure, fulfilling the requirement for supporting materials. Being a support, the structural uniqueness and N dopants of NPGR facilitate the deposition of Pt nanoparticles (Pt NPs). The Pt NPs/NPGR composites integrate the structural properties of NPGR and catalytic properties of Pt NPs. A selective and sensitive electrochemical sensor was successfully developed for sensitive determination of Tadalafil (TAD), showing a concentration range of 1.30–488.9 µM and limit of detection of 0.268 µM. 2018 Journal Article http://hdl.handle.net/20.500.11937/71549 10.1016/j.jcis.2017.10.022 Academic Press restricted
spellingShingle Salah, A.
Hassan, M.
Liu, Jian
Li, M.
Bo, X.
Ndamanisha, J.
Guo, L.
Pt nanoparticles supported on nitrogen-doped porous graphene for sensitive detection of Tadalafil
title Pt nanoparticles supported on nitrogen-doped porous graphene for sensitive detection of Tadalafil
title_full Pt nanoparticles supported on nitrogen-doped porous graphene for sensitive detection of Tadalafil
title_fullStr Pt nanoparticles supported on nitrogen-doped porous graphene for sensitive detection of Tadalafil
title_full_unstemmed Pt nanoparticles supported on nitrogen-doped porous graphene for sensitive detection of Tadalafil
title_short Pt nanoparticles supported on nitrogen-doped porous graphene for sensitive detection of Tadalafil
title_sort pt nanoparticles supported on nitrogen-doped porous graphene for sensitive detection of tadalafil
url http://hdl.handle.net/20.500.11937/71549