Evidence for the Involvement of the Master Transcription Factor NF-?B in Cancer Initiation and Progression.
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) is responsible for the regulation of a large number of genes that are involved in important physiological processes, including survival, inflammation, and immune responses. At the same time, this transcription factor can control...
| Main Authors: | Puar, Y., Shanmugam, M., Fan, L., Arfuso, Frank, Sethi, G., Tergaonkar, V. |
|---|---|
| Format: | Journal Article |
| Published: |
2018
|
| Online Access: | http://hdl.handle.net/20.500.11937/71322 |
Similar Items
NF-κB in cancer therapy
by: Li, F., et al.
Published: (2015)
by: Li, F., et al.
Published: (2015)
Role of NF-κB in tumorigenesis
by: Shanmugam, M., et al.
Published: (2013)
by: Shanmugam, M., et al.
Published: (2013)
Oleuropein induces apoptosis via abrogating NF-?B activation cascade in estrogen receptor–negative breast cancer cells
by: Liu, L., et al.
Published: (2018)
by: Liu, L., et al.
Published: (2018)
Role of RNF20 in cancer development and progression – a comprehensive review
by: Sethi, G., et al.
Published: (2018)
by: Sethi, G., et al.
Published: (2018)
Activation of the transcription factor NF-kB by Campylobacter jejuni
by: Alsayeqh, Abdullah Fayez
Published: (2007)
by: Alsayeqh, Abdullah Fayez
Published: (2007)
Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-?B signaling cascade in gastric cancer
by: Manu, K., et al.
Published: (2015)
by: Manu, K., et al.
Published: (2015)
Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds
by: Shanmugam, M., et al.
Published: (2015)
by: Shanmugam, M., et al.
Published: (2015)
Corrigendum on “Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer” [Cancer Lett. 363 (1) (2015) 28–36]
by: Manu, K., et al.
Published: (2018)
by: Manu, K., et al.
Published: (2018)
Novel tumor necrosis factor-a induced protein eight (TNFAIP8/TIPE) family: Functions and downstream targets involved in cancer progression
by: Padmavathi, G., et al.
Published: (2018)
by: Padmavathi, G., et al.
Published: (2018)
Dysregulation of Nrf2 in hepatocellular carcinoma: Role in cancer progression and chemoresistance
by: Raghunath, A., et al.
Published: (2018)
by: Raghunath, A., et al.
Published: (2018)
Colon cancer chemoresistance and chemosensitization
by: Shanmugam, M., et al.
Published: (2018)
by: Shanmugam, M., et al.
Published: (2018)
Targeting transcription factor STAT3 for cancer prevention and therapy.
by: Chai, E., et al.
Published: (2015)
by: Chai, E., et al.
Published: (2015)
First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway
by: Manu, K., et al.
Published: (2012)
by: Manu, K., et al.
Published: (2012)
Triterpenoids and sesquiterpenoids for prostate cancer therapy
by: Shanmugam, M., et al.
Published: (2016)
by: Shanmugam, M., et al.
Published: (2016)
Potential Role of Natural Compounds as Anti-Angiogenic Agents in Cancer
by: Shanmugam, M., et al.
Published: (2017)
by: Shanmugam, M., et al.
Published: (2017)
Multifaceted link between cancer and inflammation
by: Sethi, G., et al.
Published: (2012)
by: Sethi, G., et al.
Published: (2012)
Ursolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathways
by: Shanmugam, M., et al.
Published: (2012)
by: Shanmugam, M., et al.
Published: (2012)
ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and C-Myc to reduce breast cancer proliferation
by: Yuan, Y., et al.
Published: (2016)
by: Yuan, Y., et al.
Published: (2016)
Analysis of the intricate relationship between chronic inflammation and cancer
by: Chai, E., et al.
Published: (2015)
by: Chai, E., et al.
Published: (2015)
Novel 1,3,4-oxadiazole induces anticancer activity by targeting NF-κB in hepatocellular carcinoma cells
by: Mohan, C., et al.
Published: (2018)
by: Mohan, C., et al.
Published: (2018)
Harnessing downstream NF-kappaB signalling to achieve apoptosis-inducing anti-cancer-specific activity
by: Vaccarezza, Mauro, et al.
Published: (2016)
by: Vaccarezza, Mauro, et al.
Published: (2016)
Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn
by: Shanmugam, M., et al.
Published: (2018)
by: Shanmugam, M., et al.
Published: (2018)
Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn
by: Shanmugam, M., et al.
Published: (2017)
by: Shanmugam, M., et al.
Published: (2017)
The role of signal transducer and activator of transcription 3 (STAT3) and its targeted inhibition in hematological malignancies
by: Arora, L., et al.
Published: (2018)
by: Arora, L., et al.
Published: (2018)
CHIP/Stub1 functions as a tumor suppressor and represses NF-?B-mediated signaling in colorectal cancer
by: Wang, Y., et al.
Published: (2014)
by: Wang, Y., et al.
Published: (2014)
Potential anti-inflammatory and anti-cancer properties of farnesol
by: Jung, Y., et al.
Published: (2018)
by: Jung, Y., et al.
Published: (2018)
Pro-apoptotic and anti-cancer properties of diosgenin: A comprehensive and critical review
by: Sethi, G., et al.
Published: (2018)
by: Sethi, G., et al.
Published: (2018)
Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells
by: Kannaiyan, R., et al.
Published: (2011)
by: Kannaiyan, R., et al.
Published: (2011)
The role of resveratrol in cancer therapy
by: Ko, J., et al.
Published: (2017)
by: Ko, J., et al.
Published: (2017)
Pharmacological utilization of bergamottin, derived from grapefruits, in cancer prevention and therapy
by: Ko, J., et al.
Published: (2018)
by: Ko, J., et al.
Published: (2018)
N-substituted pyrido-1,4-Oxazin-3-ones induce apoptosis of hepatocellular carcinoma cells by targeting NF-kB signaling pathway
by: Mohan, C., et al.
Published: (2018)
by: Mohan, C., et al.
Published: (2018)
In vitro apoptosis induction and inhibition of NF-kB signaling pathway by biseugenol B in PC3 human prostatic cancer cells / Maryam Abbaspour Babaei
by: Maryam, Abbaspour Babaei
Published: (2018)
by: Maryam, Abbaspour Babaei
Published: (2018)
An investigation of potential prognostic indicators and biomarkers (TRAF1, NF- kB and CD14) in renal cancers / Yap Ning Yi
by: Yap, Ning Yi
Published: (2018)
by: Yap, Ning Yi
Published: (2018)
Essential oil and leaves from Lantana camara significantly ameliorate different cancer cell lines by suppressing the NF-κB pathway
by: Sajid, Arfaa, et al.
Published: (2021)
by: Sajid, Arfaa, et al.
Published: (2021)
Therapeutic potential of mushrooms: a review on NF-κB modulation in chronic inflammation
by: Amirullah, Nur Amalina, et al.
Published: (2024)
by: Amirullah, Nur Amalina, et al.
Published: (2024)
Erratum: Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-?B activation in breast and pancreatic tumor cells (Biochemical Pharmacology (2010) 80 (1553-1562))
by: Chua, A., et al.
Published: (2014)
by: Chua, A., et al.
Published: (2014)
The expanding roles of long non-coding RNAs in the regulation of cancer stem cells
by: Ma, Z., et al.
Published: (2019)
by: Ma, Z., et al.
Published: (2019)
Investigating the initiation & progression of ulcerative colitis
by: Fair, Kathryn L.
Published: (2024)
by: Fair, Kathryn L.
Published: (2024)
Severity of asthma: the role of CD25+,CD30+, NF-κB, and apoptotic markers
by: Abdulamir, Ahmed Sahib, et al.
Published: (2009)
by: Abdulamir, Ahmed Sahib, et al.
Published: (2009)
The multifaceted role of curcumin in cancer prevention and treatment
by: Shanmugam, M., et al.
Published: (2015)
by: Shanmugam, M., et al.
Published: (2015)
Similar Items
-
NF-κB in cancer therapy
by: Li, F., et al.
Published: (2015) -
Role of NF-κB in tumorigenesis
by: Shanmugam, M., et al.
Published: (2013) -
Oleuropein induces apoptosis via abrogating NF-?B activation cascade in estrogen receptor–negative breast cancer cells
by: Liu, L., et al.
Published: (2018) -
Role of RNF20 in cancer development and progression – a comprehensive review
by: Sethi, G., et al.
Published: (2018) -
Activation of the transcription factor NF-kB by Campylobacter jejuni
by: Alsayeqh, Abdullah Fayez
Published: (2007)