De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation

De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation

© 2016 The Author(s). Disruptions to neuronal mRNA translation are hypothesized to underlie human neurodevelopmental syndromes. Notably, the mRNA translation re-initiation factor DENR is a regulator of eukaryotic translation and cell growth, but its mammalian functions are unknown. Here, we report t...

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Bibliographic Details
Main Authors: Haas, M., Ngo, L., Li, S., Schleich, S., Qu, Z., Vanyai, H., Cullen, H., Cardona-Alberich, A., Gladwyn-Ng, I., Pagnamenta, A., Taylor, J., Stewart, H., Kini, U., Duncan, K., Teleman, A., Keays, D., Heng, Julian
Format: Journal Article
Published: Elsevier Inc. 2016
Online Access:http://hdl.handle.net/20.500.11937/71202

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