Pharmaceutical and Biological Evaluation of Nano Photosensitizers for Cancer Therapy
This study demonstrated the effects of novel hybrid metal oxide nanoparticles as an effective nano-photosensitizer for the photodynamic therapy against melanoma in vitro and in vivo. A strong synergistic effect was produced by the hybrid NPs and UV-A irradiation. The hybrid nanoparticles modified w...
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| Format: | Thesis |
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Curtin University
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/70565 |
| _version_ | 1848762282106945536 |
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| author | Sundara Raj, Behin |
| author_facet | Sundara Raj, Behin |
| author_sort | Sundara Raj, Behin |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | This study demonstrated the effects of novel hybrid metal oxide nanoparticles as an effective nano-photosensitizer for the photodynamic therapy against melanoma in vitro and in vivo. A strong synergistic effect was produced by the hybrid NPs and UV-A irradiation. The hybrid nanoparticles modified with folic acid enhanced cellular uptake and exhibited strong anti-tumour activity alone and with UV-A. These hybrid nanoparticles provide us better understanding in designing the semiconductor metal oxides-based nano-photosensitizers for photodynamic therapy. |
| first_indexed | 2025-11-14T10:45:05Z |
| format | Thesis |
| id | curtin-20.500.11937-70565 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:45:05Z |
| publishDate | 2018 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-705652019-08-28T07:17:48Z Pharmaceutical and Biological Evaluation of Nano Photosensitizers for Cancer Therapy Sundara Raj, Behin This study demonstrated the effects of novel hybrid metal oxide nanoparticles as an effective nano-photosensitizer for the photodynamic therapy against melanoma in vitro and in vivo. A strong synergistic effect was produced by the hybrid NPs and UV-A irradiation. The hybrid nanoparticles modified with folic acid enhanced cellular uptake and exhibited strong anti-tumour activity alone and with UV-A. These hybrid nanoparticles provide us better understanding in designing the semiconductor metal oxides-based nano-photosensitizers for photodynamic therapy. 2018 Thesis http://hdl.handle.net/20.500.11937/70565 Curtin University fulltext |
| spellingShingle | Sundara Raj, Behin Pharmaceutical and Biological Evaluation of Nano Photosensitizers for Cancer Therapy |
| title | Pharmaceutical and Biological Evaluation of Nano Photosensitizers for Cancer Therapy |
| title_full | Pharmaceutical and Biological Evaluation of Nano Photosensitizers for Cancer Therapy |
| title_fullStr | Pharmaceutical and Biological Evaluation of Nano Photosensitizers for Cancer Therapy |
| title_full_unstemmed | Pharmaceutical and Biological Evaluation of Nano Photosensitizers for Cancer Therapy |
| title_short | Pharmaceutical and Biological Evaluation of Nano Photosensitizers for Cancer Therapy |
| title_sort | pharmaceutical and biological evaluation of nano photosensitizers for cancer therapy |
| url | http://hdl.handle.net/20.500.11937/70565 |