CpxR Activates MexAB-OprM Efflux Pump Expression and Enhances Antibiotic Resistance in Both Laboratory and Clinical nalB-Type Isolates of Pseudomonas aeruginosa

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CpxR Activates MexAB-OprM Efflux Pump Expression and Enhances Antibiotic Resistance in Both Laboratory and Clinical nalB-Type Isolates of Pseudomonas aeruginosa

Resistance-Nodulation-Division (RND) efflux pumps are responsible for multidrug resistance in Pseudomonas aeruginosa. In this study, we demonstrate that CpxR, previously identified as a regulator of the cell envelope stress response in Escherichia coli, is directly involved in activation of expressi...

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Bibliographic Details
Main Authors:	Tian, Z., Yi, X., Cho, A., O'Gara, Fergal, Wang, Y.
Format:	Journal Article
Published:	Public Library of Science 2016
Online Access:	http://hdl.handle.net/20.500.11937/70012

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