In-situ secondary growth of nanocube-based Prussian-blue film as an ultrasensitive biosensor

A regular nanostructure has been widely confirmed to result ina marked improvement in material performance in biosensing applications. In the present study, a regular nanostructured Prussian blue (PB) film with two heterogeneous crystal layers was synthesized in-situ using a secondary growth method....

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Main Authors: Liu, Yu, Peng, J., Jiang, D., Chu, Z., Jin, W.
Format: Journal Article
Published: Elsevier Ltd 2017
Online Access:http://hdl.handle.net/20.500.11937/69826
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author Liu, Yu
Peng, J.
Jiang, D.
Chu, Z.
Jin, W.
author_facet Liu, Yu
Peng, J.
Jiang, D.
Chu, Z.
Jin, W.
author_sort Liu, Yu
building Curtin Institutional Repository
collection Online Access
description A regular nanostructure has been widely confirmed to result ina marked improvement in material performance in biosensing applications. In the present study, a regular nanostructured Prussian blue (PB) film with two heterogeneous crystal layers was synthesized in-situ using a secondary growth method. A PB seed layer was first controlled to form uniform cube-like crystal nuclei through an ultrasonic reaction with a single reactant. Then, well-defined 100 nm PB nanocubes were further crystallized on this seed layer using a self-assembly approach. In order to accelerate the electron transfer rate during the enzyme reaction for glucose detection, the graphene was used as the main cross-linker to immobilize glucose oxidase on the PB film. The as-prepared biosensor exhibited high electrocatalysis and electron conductivity for the detection of trace glucose with a sensitivity of 141.5 µA mM-1 cm-2, as well as excellent anti-interference ability in the presence of ascorbic acid and uric acid under a low operation potential of -0.05 V.
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publishDate 2017
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spelling curtin-20.500.11937-698262018-11-14T07:31:58Z In-situ secondary growth of nanocube-based Prussian-blue film as an ultrasensitive biosensor Liu, Yu Peng, J. Jiang, D. Chu, Z. Jin, W. A regular nanostructure has been widely confirmed to result ina marked improvement in material performance in biosensing applications. In the present study, a regular nanostructured Prussian blue (PB) film with two heterogeneous crystal layers was synthesized in-situ using a secondary growth method. A PB seed layer was first controlled to form uniform cube-like crystal nuclei through an ultrasonic reaction with a single reactant. Then, well-defined 100 nm PB nanocubes were further crystallized on this seed layer using a self-assembly approach. In order to accelerate the electron transfer rate during the enzyme reaction for glucose detection, the graphene was used as the main cross-linker to immobilize glucose oxidase on the PB film. The as-prepared biosensor exhibited high electrocatalysis and electron conductivity for the detection of trace glucose with a sensitivity of 141.5 µA mM-1 cm-2, as well as excellent anti-interference ability in the presence of ascorbic acid and uric acid under a low operation potential of -0.05 V. 2017 Journal Article http://hdl.handle.net/20.500.11937/69826 10.1016/j.pnsc.2017.04.005 http://creativecommons.org/licenses/by-nc-nd/4.0/ Elsevier Ltd fulltext
spellingShingle Liu, Yu
Peng, J.
Jiang, D.
Chu, Z.
Jin, W.
In-situ secondary growth of nanocube-based Prussian-blue film as an ultrasensitive biosensor
title In-situ secondary growth of nanocube-based Prussian-blue film as an ultrasensitive biosensor
title_full In-situ secondary growth of nanocube-based Prussian-blue film as an ultrasensitive biosensor
title_fullStr In-situ secondary growth of nanocube-based Prussian-blue film as an ultrasensitive biosensor
title_full_unstemmed In-situ secondary growth of nanocube-based Prussian-blue film as an ultrasensitive biosensor
title_short In-situ secondary growth of nanocube-based Prussian-blue film as an ultrasensitive biosensor
title_sort in-situ secondary growth of nanocube-based prussian-blue film as an ultrasensitive biosensor
url http://hdl.handle.net/20.500.11937/69826