Admissions for antibiotic-resistant infections in cancer patients during first year of cancer diagnosis: a cross-sectional study
In this study, linked Western Australian health data were used to determine presence of an antibiotic-resistant infection (ABRI) for all people diagnosed with a primary invasive cancer in 2009. Of 10 858 cancer cases, 154 (1.42%) had an ABRI. Patients with an ABRI were older (71.5 vs 66 years), and...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal Article |
| Published: |
Blackwell Publishing
2017
|
| Online Access: | http://hdl.handle.net/20.500.11937/69623 |
| _version_ | 1848762090037182464 |
|---|---|
| author | Slavova-Azmanova, N. Haddow, L. Hohnen, H. Coombs, Geoffrey Robinson, J. Ives, A. |
| author_facet | Slavova-Azmanova, N. Haddow, L. Hohnen, H. Coombs, Geoffrey Robinson, J. Ives, A. |
| author_sort | Slavova-Azmanova, N. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | In this study, linked Western Australian health data were used to determine presence of an antibiotic-resistant infection (ABRI) for all people diagnosed with a primary invasive cancer in 2009. Of 10 858 cancer cases, 154 (1.42%) had an ABRI. Patients with an ABRI were older (71.5 vs 66 years), and more had died in the year following diagnosis (37.7 vs 20.2%, P < 0.001). The ABRI cohort had a higher proportion of colorectal, genitourinary and haematological cancers (19.5 vs 11.9%; 14.3 vs 9.7% and 16.9 vs 5.8%, respectively). Hospital admissions with an ABRI were longer (22.3 vs 2.9 days, P < 0.001) and had a higher proportion of unplanned admissions (60.3 vs 15.2%), admissions through emergency department (36.8 vs 8.3%) and intensive care admissions (14.9 vs 1.7%, P < 0.001). Patients with solid tumours who developed an ABRI were more likely to have received chemotherapy (35.9 vs 27.8%, P = 0.04). In haematological cancer patients, a greater proportion of the admissions with an ABRI occurred after radiation therapy or chemotherapy (P = 0.01 and P = 0.005, respectively). This study is the first to report population-level data on ABRI in cancer patients. Patients with an ABRI had more hospital admissions and poorer outcomes. |
| first_indexed | 2025-11-14T10:42:02Z |
| format | Journal Article |
| id | curtin-20.500.11937-69623 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:42:02Z |
| publishDate | 2017 |
| publisher | Blackwell Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-696232018-09-27T06:36:45Z Admissions for antibiotic-resistant infections in cancer patients during first year of cancer diagnosis: a cross-sectional study Slavova-Azmanova, N. Haddow, L. Hohnen, H. Coombs, Geoffrey Robinson, J. Ives, A. In this study, linked Western Australian health data were used to determine presence of an antibiotic-resistant infection (ABRI) for all people diagnosed with a primary invasive cancer in 2009. Of 10 858 cancer cases, 154 (1.42%) had an ABRI. Patients with an ABRI were older (71.5 vs 66 years), and more had died in the year following diagnosis (37.7 vs 20.2%, P < 0.001). The ABRI cohort had a higher proportion of colorectal, genitourinary and haematological cancers (19.5 vs 11.9%; 14.3 vs 9.7% and 16.9 vs 5.8%, respectively). Hospital admissions with an ABRI were longer (22.3 vs 2.9 days, P < 0.001) and had a higher proportion of unplanned admissions (60.3 vs 15.2%), admissions through emergency department (36.8 vs 8.3%) and intensive care admissions (14.9 vs 1.7%, P < 0.001). Patients with solid tumours who developed an ABRI were more likely to have received chemotherapy (35.9 vs 27.8%, P = 0.04). In haematological cancer patients, a greater proportion of the admissions with an ABRI occurred after radiation therapy or chemotherapy (P = 0.01 and P = 0.005, respectively). This study is the first to report population-level data on ABRI in cancer patients. Patients with an ABRI had more hospital admissions and poorer outcomes. 2017 Journal Article http://hdl.handle.net/20.500.11937/69623 10.1111/imj.13609 Blackwell Publishing restricted |
| spellingShingle | Slavova-Azmanova, N. Haddow, L. Hohnen, H. Coombs, Geoffrey Robinson, J. Ives, A. Admissions for antibiotic-resistant infections in cancer patients during first year of cancer diagnosis: a cross-sectional study |
| title | Admissions for antibiotic-resistant infections in cancer patients during first year of cancer diagnosis: a cross-sectional study |
| title_full | Admissions for antibiotic-resistant infections in cancer patients during first year of cancer diagnosis: a cross-sectional study |
| title_fullStr | Admissions for antibiotic-resistant infections in cancer patients during first year of cancer diagnosis: a cross-sectional study |
| title_full_unstemmed | Admissions for antibiotic-resistant infections in cancer patients during first year of cancer diagnosis: a cross-sectional study |
| title_short | Admissions for antibiotic-resistant infections in cancer patients during first year of cancer diagnosis: a cross-sectional study |
| title_sort | admissions for antibiotic-resistant infections in cancer patients during first year of cancer diagnosis: a cross-sectional study |
| url | http://hdl.handle.net/20.500.11937/69623 |