Alcohol pharmacokinetics, decision making and folk wisdom: A reply to Moxnes and Jensen (2009)

Moxnes and Jensen (2009) present a study of decision making under conditions of uncertainty using a computerised simulation of alcohol pharmacokinetics. In their article, they conclude that their findings challenge the ‘folk wisdom’ that advises against drinking on an empty stomach. We contend that...

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Main Authors: Moss, A., Dyer, K., Albery, I., Allsop, Steve, Kypri, K., Erskine, J., Mackintosh, D.
Format: Journal Article
Published: Elsevier Ireland Ltd 2010
Online Access:http://hdl.handle.net/20.500.11937/6923
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author Moss, A.
Dyer, K.
Albery, I.
Allsop, Steve
Kypri, K.
Erskine, J.
Mackintosh, D.
author_facet Moss, A.
Dyer, K.
Albery, I.
Allsop, Steve
Kypri, K.
Erskine, J.
Mackintosh, D.
author_sort Moss, A.
building Curtin Institutional Repository
collection Online Access
description Moxnes and Jensen (2009) present a study of decision making under conditions of uncertainty using a computerised simulation of alcohol pharmacokinetics. In their article, they conclude that their findings challenge the ‘folk wisdom’ that advises against drinking on an empty stomach. We contend that this is a problematic conclusion for three reasons: (1) the study and findings presented in their paper are simply not sufficient to allow one to, even tentatively, draw such a conclusion; (2) the conclusion is contrary to basic pharmacological knowledge concerning alcohol absorption, metabolism and the implications for peak blood alcohol concentration; and (3) the implications for understanding the process of decision making while alcohol intoxicated are not considered in the study. The Moxnes and Jensen (2009) study did not involve alcohol administration and is therefore an examination of decision making in situations of uncertainty rather than a specific exploration of drinking-related decision making. Recent formulations of the effects of alcohol on cognitive processing would lead to different conclusions than those presented by Moxnes and Jensen (2009). We conclude by suggesting our understanding of the implications of the study.
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institution Curtin University Malaysia
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publishDate 2010
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spelling curtin-20.500.11937-69232017-09-13T16:02:57Z Alcohol pharmacokinetics, decision making and folk wisdom: A reply to Moxnes and Jensen (2009) Moss, A. Dyer, K. Albery, I. Allsop, Steve Kypri, K. Erskine, J. Mackintosh, D. Moxnes and Jensen (2009) present a study of decision making under conditions of uncertainty using a computerised simulation of alcohol pharmacokinetics. In their article, they conclude that their findings challenge the ‘folk wisdom’ that advises against drinking on an empty stomach. We contend that this is a problematic conclusion for three reasons: (1) the study and findings presented in their paper are simply not sufficient to allow one to, even tentatively, draw such a conclusion; (2) the conclusion is contrary to basic pharmacological knowledge concerning alcohol absorption, metabolism and the implications for peak blood alcohol concentration; and (3) the implications for understanding the process of decision making while alcohol intoxicated are not considered in the study. The Moxnes and Jensen (2009) study did not involve alcohol administration and is therefore an examination of decision making in situations of uncertainty rather than a specific exploration of drinking-related decision making. Recent formulations of the effects of alcohol on cognitive processing would lead to different conclusions than those presented by Moxnes and Jensen (2009). We conclude by suggesting our understanding of the implications of the study. 2010 Journal Article http://hdl.handle.net/20.500.11937/6923 10.1016/j.drugalcdep.2010.01.002 Elsevier Ireland Ltd restricted
spellingShingle Moss, A.
Dyer, K.
Albery, I.
Allsop, Steve
Kypri, K.
Erskine, J.
Mackintosh, D.
Alcohol pharmacokinetics, decision making and folk wisdom: A reply to Moxnes and Jensen (2009)
title Alcohol pharmacokinetics, decision making and folk wisdom: A reply to Moxnes and Jensen (2009)
title_full Alcohol pharmacokinetics, decision making and folk wisdom: A reply to Moxnes and Jensen (2009)
title_fullStr Alcohol pharmacokinetics, decision making and folk wisdom: A reply to Moxnes and Jensen (2009)
title_full_unstemmed Alcohol pharmacokinetics, decision making and folk wisdom: A reply to Moxnes and Jensen (2009)
title_short Alcohol pharmacokinetics, decision making and folk wisdom: A reply to Moxnes and Jensen (2009)
title_sort alcohol pharmacokinetics, decision making and folk wisdom: a reply to moxnes and jensen (2009)
url http://hdl.handle.net/20.500.11937/6923