BDNF Val66Met in preclinical Alzheimer's disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF

QR Code

BDNF Val66Met in preclinical Alzheimer's disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF

Copyright Â© International Psychogeriatric Association 2017. Background: The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism Met allele exacerbates amyloid (AÎ²) related decline in episodic memory (EM) and hippocampal volume (HV) over 36-54 months in preclinical Alzheimer's disea...

Full description

Bibliographic Details
Main Authors:	Lim, Y., Rainey-Smith, S., Laws, Simon, Gupta, V., Porter, T., Bourgeat, P., Ames, D., Fowler, C., Salvado, O., Villemagne, V., Rowe, C., Masters, C., Zhou, X., Martins, R., Maruff, P.
Format:	Journal Article
Published:	Cambridge University Press 2017
Online Access:	http://hdl.handle.net/20.500.11937/68772

Similar Items

Single nucleotide polymorphism of BDNF Val66Met (rs6265) and its association to neuropsychiatric disorders
by: Asraa Faris, et al.
Published: (2020)

ß-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and Men
by: Holmes, S., et al.
Published: (2016)

Changes of GABA receptor and immunoreactivity modification of IP3 & BDNF-TrkB in KA-induced rat epileptogenic hippocampal neuronal culture
by: Nei, Chong Pei
Published: (2018)

Klotho allele status is not associated with Aß and APOE e4–related cognitive decline in preclinical Alzheimer's disease
by: Porter, T., et al.
Published: (2019)

Effect of Tie-2 conditional deletion of BDNF on atherosclerosis in the ApoE null mutant mouse
by: Norata, Giuseppe, et al.
Published: (2012)

Relationship of brain derived neurotrophic factor (BDNF) DNA methylation with schizophrenia
by: Abd. Rahim, Nour El Huda, et al.
Published: (2016)

What keeps a body moving? The brain-derived neurotrophic factor val66met polymorphism and intrinsic motivation to exercise in humans
by: Caldwell Hooper, A., et al.
Published: (2014)

Utility of an Alzheimer's Disease Risk-Weighted Polygenic Risk Score for Predicting Rates of Cognitive Decline in Preclinical Alzheimer's Disease: A Prospective Longitudinal Study.
by: Porter, T., et al.
Published: (2018)

A Polygenic Risk Score Derived From Episodic Memory Weighted Genetic Variants Is Associated With Cognitive Decline in Preclinical Alzheimer's Disease
by: Porter, T., et al.
Published: (2018)

KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aß-amyloid burden
by: Porter, T., et al.
Published: (2018)

Cognition and beta-amyloid in preclinical Alzheimer's disease: Data from the AIBL study
by: Pike, K., et al.
Published: (2011)

Development and validation of high resolution melting assays for high-throughput screening of BDNF rs6265 and DAT1 rs40184
by: Faris, Asraa, et al.
Published: (2018)

Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study.
by: Burnham, S., et al.
Published: (2016)

Intravitreal application of AAV-BDNF or mutant AAV-CRMP2 protects retinal ganglion cells and stabilizes axons and myelin after partial optic nerve injury
by: Chiha, Wissam, et al.
Published: (2020)

Amyloid ß–associated cognitive decline in the absence of clinical disease progression and systemic illness
by: Harrington, K., et al.
Published: (2017)

Trajectories of depressive and anxiety symptoms in older adults: a 6-year prospective cohort study
by: Holmes, S., et al.
Published: (2018)

Targeted delivery of BDNF-loaded poly (lactide-co-glycolide) nanoparticle to the brain: penetration through blood brain barrier and neuroprotective effect in stroke / Siti Norsyafika Kamarudin
by: Kamarudin, Siti Norsyafika
Published: (2019)

Enhancement of BDNF Concentration and Restoration of the Hypothalamic-Pituitary-Adrenal Axis Accompany Reduced Depressive-Like Behaviour in Stressed Ovariectomised Rats Treated with Either Tualang Honey or Estrogen
by: Al-Rahbi, Badriya, et al.
Published: (2014)

The correlation of plasma levels of Brain Derived Neurotrophic Factor (BDNF) and C-tau protein with the Simplified Acute Physiology Score II (SAPS II) in critically ill patients
by: Nik, Wan Nurul 'Izzati Wan
Published: (2013)

Structural changes, expression of dream, BDNF and CREB proteins in the hippocampus; and spatial learning and memory of rapid eye movement (REM) sleep-deprived rats upon acute nicotine treatment
by: Rashid, Norlinda Abd
Published: (2018)

Changes of dream and BDNF proteins expressions, pro-inflammatory and oxidative stress levels spinal cord of streptozotocin-induced painful diabetic neuropathy rats upon minocycline and ifenprodil treatments
by: Ismail, Che Aishah Nazariah
Published: (2018)

Stingless bee honey improves spatial memory in mice, probably associated with brain-derived neurotrophic factor (BDNF) and Inositol 1,4,5- triphosphate receptor type 1 (Itpr1) genes
by: Zulkifli, Fairuz Nabila, et al.
Published: (2019)

Prevalence of Hypertension in University Students and Association of Catechol-O Methyltransferase (Val158met) and Dopamine D2 Receptor (Taq1a) Polymorphism with Hypertension
by: Gan, Kelvin
Published: (2016)

ProVal: A new autonomous profiling float for high quality radiometric measurements
by: Leymarie, E., et al.
Published: (2018)

Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults
by: Laws, S., et al.
Published: (2017)

Rhizome oil of Curcuma ochrorhiza Val.
by: Mohd Sirat, Hasnah, et al.
Published: (1997)

The rhizome oil of Kaempferia rotunda Val
by: Sirat, Hasnah Mohd, et al.
Published: (2005)

Hippocampal neural disinhibition causes attentional and memory deficits
by: McGarrity, Stephanie, et al.
Published: (2017)

Can You Jive? When Michael Met Sophie
by: Yiannakis, John
Published: (2013)

Partial melting of metabasic rocks in Val Strona di Omegna, Ivrea Zone, northern Italy
by: Kunz, B., et al.
Published: (2014)

Preclinical evidence of Malay traditional herbal supplement for diabetes
by: Abdul Majid, Fadzilah Adibah, et al.
Published: (2016)

Preclinical safety evaluation of WJMSCs and their secretome
by: Premasangery Kathivaloo,, et al.
Published: (2025)

Part IV Italy: Case 12 Passeiertal/Val Passiria
by: Volgger, Michael, et al.
Published: (2015)

Determination of the role of synechococcus rubisco residue val-425 in chimeras
by: Wong, Clara Chia Ci
Published: (2023)

66 taska kerajaan bakal dibuka
by: Mohammad, Hidayah
Published: (2019)

Potential benefits of edible berries in the management of aerodigestive and gastrointestinal tract cancers: Preclinical and clinical evidence
by: Bishayee, A., et al.
Published: (2016)

c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression
by: Sim, W.J., et al.
Published: (2019)

Identification of common variants associated with human hippocampal and intracranial volumes
by: Stein, J., et al.
Published: (2012)

Mitragynine (Kratom) impairs spatial learning and hippocampal synaptic transmission in rats
by: Hassan, Zurina, et al.
Published: (2019)

Management of ErbB2-positive breast cancer: Insights from preclinical and clinical studies with lapatinib
by: Vogel, C., et al.
Published: (2010)

Cannot write session to /tmp/vufind_sessions/sess_02jcarvekqf0fevnhft8o97hge