Determination of the mutagenic potential of commonly marketed Ghanaian medicinal plant formulations using the bacterial reverse mutation assay
The mutagenic potential of nine commonly marketed Ghanaian medicinal plant aqueous extract formulations determined using the bacterial reverse mutation assay (Ames test) were found to be non-mutagenic. In contrast, one extract, E8 was found to be anti-mutagenic as determined using either a frameshif...
| Main Author: | |
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| Format: | Thesis |
| Language: | English |
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Curtin University
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/687 |
| _version_ | 1848743451081834496 |
|---|---|
| author | Senayah, Fidelia |
| author_facet | Senayah, Fidelia |
| author_sort | Senayah, Fidelia |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The mutagenic potential of nine commonly marketed Ghanaian medicinal plant aqueous extract formulations determined using the bacterial reverse mutation assay (Ames test) were found to be non-mutagenic. In contrast, one extract, E8 was found to be anti-mutagenic as determined using either a frameshift or a base pair substitution mutant of S. typhimurium in the metabolic activation system. E8 was also found to possess antimicrobial activity against Moraxella catarrhalis. |
| first_indexed | 2025-11-14T05:45:46Z |
| format | Thesis |
| id | curtin-20.500.11937-687 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T05:45:46Z |
| publishDate | 2015 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-6872017-02-20T06:42:16Z Determination of the mutagenic potential of commonly marketed Ghanaian medicinal plant formulations using the bacterial reverse mutation assay Senayah, Fidelia The mutagenic potential of nine commonly marketed Ghanaian medicinal plant aqueous extract formulations determined using the bacterial reverse mutation assay (Ames test) were found to be non-mutagenic. In contrast, one extract, E8 was found to be anti-mutagenic as determined using either a frameshift or a base pair substitution mutant of S. typhimurium in the metabolic activation system. E8 was also found to possess antimicrobial activity against Moraxella catarrhalis. 2015 Thesis http://hdl.handle.net/20.500.11937/687 en Curtin University fulltext |
| spellingShingle | Senayah, Fidelia Determination of the mutagenic potential of commonly marketed Ghanaian medicinal plant formulations using the bacterial reverse mutation assay |
| title | Determination of the mutagenic potential of commonly marketed Ghanaian medicinal plant formulations using the bacterial reverse mutation assay |
| title_full | Determination of the mutagenic potential of commonly marketed Ghanaian medicinal plant formulations using the bacterial reverse mutation assay |
| title_fullStr | Determination of the mutagenic potential of commonly marketed Ghanaian medicinal plant formulations using the bacterial reverse mutation assay |
| title_full_unstemmed | Determination of the mutagenic potential of commonly marketed Ghanaian medicinal plant formulations using the bacterial reverse mutation assay |
| title_short | Determination of the mutagenic potential of commonly marketed Ghanaian medicinal plant formulations using the bacterial reverse mutation assay |
| title_sort | determination of the mutagenic potential of commonly marketed ghanaian medicinal plant formulations using the bacterial reverse mutation assay |
| url | http://hdl.handle.net/20.500.11937/687 |