Isolation and purification of protein (Conglutin-γ) from lupin seeds

This research focuses on the development of a scalable process for purification of ‘glucose modulating bioactive’, γ-conglutin from lupin seeds. Selective extraction at acidic pH and cation exchange chromatography with an intermediate pH modulation step enabled the isolation of γ-conglutin with hig...

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Main Author: Mane, Sharmilee
Format: Thesis
Published: Curtin University 2017
Online Access:http://hdl.handle.net/20.500.11937/68387
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author Mane, Sharmilee
author_facet Mane, Sharmilee
author_sort Mane, Sharmilee
building Curtin Institutional Repository
collection Online Access
description This research focuses on the development of a scalable process for purification of ‘glucose modulating bioactive’, γ-conglutin from lupin seeds. Selective extraction at acidic pH and cation exchange chromatography with an intermediate pH modulation step enabled the isolation of γ-conglutin with highest reported purity in minimum process steps. The effect of process parameters was optimized to obtain the maximum purity. γ-Conglutin purified by the developed process was confirmed for its identity by different analytical techniques.
first_indexed 2025-11-14T10:37:21Z
format Thesis
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T10:37:21Z
publishDate 2017
publisher Curtin University
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-683872023-06-13T04:12:52Z Isolation and purification of protein (Conglutin-γ) from lupin seeds Mane, Sharmilee This research focuses on the development of a scalable process for purification of ‘glucose modulating bioactive’, γ-conglutin from lupin seeds. Selective extraction at acidic pH and cation exchange chromatography with an intermediate pH modulation step enabled the isolation of γ-conglutin with highest reported purity in minimum process steps. The effect of process parameters was optimized to obtain the maximum purity. γ-Conglutin purified by the developed process was confirmed for its identity by different analytical techniques. 2017 Thesis http://hdl.handle.net/20.500.11937/68387 Curtin University fulltext
spellingShingle Mane, Sharmilee
Isolation and purification of protein (Conglutin-γ) from lupin seeds
title Isolation and purification of protein (Conglutin-γ) from lupin seeds
title_full Isolation and purification of protein (Conglutin-γ) from lupin seeds
title_fullStr Isolation and purification of protein (Conglutin-γ) from lupin seeds
title_full_unstemmed Isolation and purification of protein (Conglutin-γ) from lupin seeds
title_short Isolation and purification of protein (Conglutin-γ) from lupin seeds
title_sort isolation and purification of protein (conglutin-γ) from lupin seeds
url http://hdl.handle.net/20.500.11937/68387