Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea

Study Objectives: (1) To describe the incidence rate of motor vehicle crashes (MVCs) in patients with obstructive sleep apnea (OSA); and (2) to investigate MVC risk factors in OSA patients. Methods: A retrospective case-series observational study was conducted using data from the West Australian Sle...

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Main Authors: Ward, Kim, Hillman, D., James, A., Bremner, A., Simpson, L., Cooper, M., Palmer, L., Fedson, A., Mukherjee, S.
Format: Journal Article
Published: 2013
Online Access:http://hdl.handle.net/20.500.11937/68171
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author Ward, Kim
Hillman, D.
James, A.
Bremner, A.
Simpson, L.
Cooper, M.
Palmer, L.
Fedson, A.
Mukherjee, S.
author_facet Ward, Kim
Hillman, D.
James, A.
Bremner, A.
Simpson, L.
Cooper, M.
Palmer, L.
Fedson, A.
Mukherjee, S.
author_sort Ward, Kim
building Curtin Institutional Repository
collection Online Access
description Study Objectives: (1) To describe the incidence rate of motor vehicle crashes (MVCs) in patients with obstructive sleep apnea (OSA); and (2) to investigate MVC risk factors in OSA patients. Methods: A retrospective case-series observational study was conducted using data from the West Australian Sleep Health Study at a tertiary hospital-based sleep clinic. Participants were patients (N = 2,673) referred for assessment of suspected sleep disordered breathing. Questionnaire data were collected including age, sex, years of driving, near-misses and MVCs, sleepiness, and consumption of alcohol and caffeinated drinks. Overnight laboratory-based polysomnography was performed using standard methodology. 1 Poisson univariate and negative binomial multivariable regression models were used to investigate associations between risk factors and MVC and nearmiss risk in patients with untreated OSA. Results: In patients with untreated OSA, the crash rate was 0.06 MVC/person-year compared with the general community crash rate of 0.02 MVC/person-year. The rate ratio comparing very sleepy men with normal men was 4.68 (95% CI 3.07, 7.14) for near-misses and 1.27 (95% CI 1.00, 1.61) for crashes, after adjusting for confounders. In women there was a signifi cant association with sleepiness score (p = 0.02) but no dose effect across quartiles. Conclusions: Untreated OSA is associated with an increased risk of near-misses in men and women and an increased risk of MVCs in very sleepy men. There is a strong association between excessive daytime sleepiness and increased report of near-misses. Our data support the observation that it is those patients with increased sleepiness regardless of OSA severity who are most at risk.
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spelling curtin-20.500.11937-681712018-05-18T08:07:30Z Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea Ward, Kim Hillman, D. James, A. Bremner, A. Simpson, L. Cooper, M. Palmer, L. Fedson, A. Mukherjee, S. Study Objectives: (1) To describe the incidence rate of motor vehicle crashes (MVCs) in patients with obstructive sleep apnea (OSA); and (2) to investigate MVC risk factors in OSA patients. Methods: A retrospective case-series observational study was conducted using data from the West Australian Sleep Health Study at a tertiary hospital-based sleep clinic. Participants were patients (N = 2,673) referred for assessment of suspected sleep disordered breathing. Questionnaire data were collected including age, sex, years of driving, near-misses and MVCs, sleepiness, and consumption of alcohol and caffeinated drinks. Overnight laboratory-based polysomnography was performed using standard methodology. 1 Poisson univariate and negative binomial multivariable regression models were used to investigate associations between risk factors and MVC and nearmiss risk in patients with untreated OSA. Results: In patients with untreated OSA, the crash rate was 0.06 MVC/person-year compared with the general community crash rate of 0.02 MVC/person-year. The rate ratio comparing very sleepy men with normal men was 4.68 (95% CI 3.07, 7.14) for near-misses and 1.27 (95% CI 1.00, 1.61) for crashes, after adjusting for confounders. In women there was a signifi cant association with sleepiness score (p = 0.02) but no dose effect across quartiles. Conclusions: Untreated OSA is associated with an increased risk of near-misses in men and women and an increased risk of MVCs in very sleepy men. There is a strong association between excessive daytime sleepiness and increased report of near-misses. Our data support the observation that it is those patients with increased sleepiness regardless of OSA severity who are most at risk. 2013 Journal Article http://hdl.handle.net/20.500.11937/68171 10.5664/jcsm.3072 restricted
spellingShingle Ward, Kim
Hillman, D.
James, A.
Bremner, A.
Simpson, L.
Cooper, M.
Palmer, L.
Fedson, A.
Mukherjee, S.
Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea
title Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea
title_full Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea
title_fullStr Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea
title_full_unstemmed Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea
title_short Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea
title_sort excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea
url http://hdl.handle.net/20.500.11937/68171