Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

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Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

Accumulating evidence(s) indicate that CXCL12-CXCR4 signaling cascade plays an important role in the process of invasion and metastasis that accounts for more than 80% of deaths in hepatocellular carcinoma (HCC) patients. Thus, identification of novel agents that can downregulate CXCR4 expression an...

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Bibliographic Details
Main Authors:	Manu, K., Shanmugam, M., Ong, T., Subramahniam, A., Siveen, K., Perumal, E., Samy, R., Bist, P., Lim, L., Kumar, Alan Prem, Hui, K., Sethi, G.
Format:	Journal Article
Published:	Public Library of Science 2013
Online Access:	http://hdl.handle.net/20.500.11937/6812

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