Transdifferentiation of pancreatic progenitor cells to hepatocyte-like cells is not serum-dependent when facilitated by extracellular matrix proteins

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Transdifferentiation of pancreatic progenitor cells to hepatocyte-like cells is not serum-dependent when facilitated by extracellular matrix proteins

The rising prevalence of chronic liver disease, coupled with a permanent shortage of organs for liver transplantation, has sparked enormous interest in alternative treatment strategies. Previous protocols to generate hepatocyte-like cells (HLCs) via pancreas-to-liver transdifferentiation have utilis...

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Bibliographic Details
Main Authors:	Gratte, F., Pasic, S., Olynyk, John, Yeoh, G., Tosh, D., Coombe, Deidre, Tirnitz-Parker, Nina
Format:	Journal Article
Published:	Nature Publishing Group 2018
Online Access:	http://hdl.handle.net/20.500.11937/68093

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